Lwebuga-Mukasa Jamson S, Oyana Tonny J, Wydro Paulette
Centre for Asthma and Environmental Exposure, Department of Internal Medicine, Kaleida Health Buffalo General Division, UB School of Medicine and Biomedical Sciences 100 High Street, Buffalo, USA.
J Epidemiol Community Health. 2004 Nov;58(11):951-7. doi: 10.1136/jech.2003.015750.
The aim of this study is to identify risk factors for asthma prevalence and chronic respiratory illnesses in Buffalo's neighbourhoods after previous studies reported increased levels of asthma among residents on Buffalo's west side.
Cross sectional surveys.
Buffalo neighbourhoods along a US-Canada border crossing point.
A systematic random survey of 82% of the 2000 targeted households was conducted between January and August 2002.
A multivariate logistic regression model shows that the risk of persons with asthma and chronic respiratory illnesses is significantly (p< or =0.05) high among children and young adults living in Buffalo's west side, newer housing units, and of Latino ethnicity. In a separate analysis of the nine risk factors, it was observed that location, gender, age, and race were significant risk factors even after adjusting for age of housing, pets, moulds, animal trigger, and smoking.
These findings confirm the hypothesis that a considerable risk of asthma and chronic respiratory illnesses exists particularly among Buffalo's west side residents. Further evaluation of these risk factors is warranted to determine the severity of asthma and the reasons for such a significant disease burden.
在先前的研究报告称布法罗西区居民哮喘患病率上升之后，本研究旨在确定布法罗各社区哮喘患病率和慢性呼吸道疾病的风险因素。
横断面调查。
美国与加拿大边境过境点沿线的布法罗社区。
2002年1月至8月期间，对2000户目标家庭中的82%进行了系统随机调查。
多变量逻辑回归模型显示，居住在布法罗西区、居住在较新住房单元且为拉丁裔的儿童和年轻人中，患哮喘和慢性呼吸道疾病的风险显著较高（p≤0.05）。在对九个风险因素进行单独分析时发现，即使在对住房年龄、宠物、霉菌、动物诱因和吸烟进行调整之后，居住地点、性别、年龄和种族仍是显著的风险因素。
这些发现证实了这样一种假设，即哮喘和慢性呼吸道疾病存在相当大的风险，尤其是在布法罗西区居民中。有必要对这些风险因素进行进一步评估，以确定哮喘的严重程度以及如此重大疾病负担的原因。
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