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周末入住重症监护病房患者的医院死亡率。

The hospital mortality of patients admitted to the ICU on weekends.

作者信息

Ensminger S Allen, Morales Ian J, Peters Steve G, Keegan Mark T, Finkielman Javier D, Lymp James F, Afessa Bekele

机构信息

Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA.

出版信息

Chest. 2004 Oct;126(4):1292-8. doi: 10.1378/chest.126.4.1292.

Abstract

STUDY OBJECTIVES

Previous studies have suggested that patients are more likely to die in the hospital if they are admitted on a weekend than on a weekday. This study was conducted to determine whether weekend admission to the ICU increases the risk of dying in the hospital.

DESIGN

Retrospective cohort study.

SETTING

ICU of a single tertiary care medical center.

PATIENTS

A total of 29,084 patients admitted to medical, surgical, and multispecialty ICUs from October 1994 through September 2002.

INTERVENTIONS

None.

MEASUREMENTS AND RESULTS

The weekend ICU admissions comprised 27.9% of all ICU admissions (8,108 ICU admissions). The overall hospital mortality rate was 8.2% (2,385 deaths). Weekend ICU admission was associated with a higher unadjusted hospital mortality rate than that for weekday ICU admission (11.3% vs 7.0%, respectively; odds ratio [OR], 1.70; 95% confidence interval [CI], 1.55 to 1.85). In multivariable analyses controlling for the factors associated with mortality such as APACHE (acute physiology and chronic health evaluation) III predicted mortality rate, ICU admission source, and intensity of treatment, no statistically significant difference in hospital mortality was found between weekend and weekday admissions in the overall study population (OR, 1.06; 95% CI, 0.95 to 1.17). For weekend ICU admissions, the observed hospital mortality rates of the medical, multispecialty, and surgical ICUs were 15.2%, 17.2%, and 6.4%, respectively, and for weekday ICU admissions the rates were 16.3%, 10.1%, and 3.5%, respectively. Subgroup analyses showed that weekend ICU admission was associated with higher adjusted hospital mortality rates than was weekday ICU admission in the surgical ICU (OR, 1.23; 95% CI, 1.03 to 1.48), but not in the medical or multispecialty ICUs.

CONCLUSIONS

The overall adjusted hospital mortality rate of patients admitted to the ICU on a weekend was not higher than that of patients admitted on a weekday. However, weekend ICU admission to the surgical ICU was associated with an increased hospital mortality rate.

摘要

研究目的

以往研究表明,与工作日入院相比,患者在周末入院时更有可能在医院死亡。本研究旨在确定重症监护病房(ICU)周末入院是否会增加医院死亡风险。

设计

回顾性队列研究。

地点

一家三级医疗中心的ICU。

患者

1994年10月至2002年9月期间,共有29084名患者入住内科、外科和多专科ICU。

干预措施

无。

测量与结果

周末ICU入院患者占所有ICU入院患者的27.9%(8108例ICU入院患者)。总体医院死亡率为8.2%(2385例死亡)。与工作日ICU入院相比,周末ICU入院的未调整医院死亡率更高(分别为11.3%和7.0%;优势比[OR]为1.70;95%置信区间[CI]为1.55至1.85)。在多变量分析中,控制了与死亡率相关的因素,如急性生理与慢性健康评估(APACHE)III预测死亡率、ICU入院来源和治疗强度,在总体研究人群中,周末和工作日入院的医院死亡率在统计学上没有显著差异(OR为1.06;95%CI为0.95至1.17)。对于周末ICU入院患者,内科、多专科和外科ICU的观察到的医院死亡率分别为15.2%、17.2%和6.4%,而对于工作日ICU入院患者,这些比率分别为16.3%、10.1%和3.5%。亚组分析表明,在外科ICU中,周末ICU入院与经调整后的医院死亡率高于工作日ICU入院相关(OR为1.23;95%CI为1.03至1.48),但在内科或多专科ICU中并非如此。

结论

周末入住ICU患者的总体调整后医院死亡率并不高于工作日入院患者。然而,周末入住外科ICU与医院死亡率增加相关。

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