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2000 年至 2011 年基于人群的诊断为胃肠道出血性血管发育不良患者的住院周末结局研究。

In-hospital weekend outcomes in patients diagnosed with bleeding gastroduodenal angiodysplasia: a population-based study, 2000 to 2011.

机构信息

Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, California, USA.

Division of Medicine and Gastroenterology, Loma Linda VA Medical Center, Loma Linda, California, USA.

出版信息

Gastrointest Endosc. 2016 Sep;84(3):416-23. doi: 10.1016/j.gie.2016.02.046. Epub 2016 Mar 10.

Abstract

BACKGROUND AND AIMS

GI angiodysplastic (GIAD) lesions are an important cause of blood loss throughout the GI tract, particularly in elderly persons. The aim of this study was to determine whether mortality rates in patients with GIAD were higher for weekend compared with weekday hospital admissions.

METHODS

We performed a retrospective study using the National Inpatient Sample database from 2000 to 2011 including inpatients with an International Classification of Diseases, Ninth Revision, Clinical Modification code for gastrointestinal GIAD (code 537.82 or 537.83). We assessed rates of delayed endoscopy (examinations performed >24 hours after admission), intensive care unit (ICU) admissions, and in-hospital mortality rates. Bivariate and multivariate logistic regression analyses were performed to identify risk factors for mortality.

RESULTS

There were 85,971 discharges for GIAD between 2000 and 2011, of which 69,984 (81%) were weekday hospital admissions and 15,987 (19%) were weekend admissions. Patients with weekend versus weekday admissions were more likely to undergo delayed endoscopic examination (35% vs 26%, P ≤ .0001). Mortality rates were higher for patients with weekend admissions (2% vs 1%, P = .0002). The adjusted odds ratio (aOR) for inpatient mortality associated with weekend admissions was elevated (2.4; 95% confidence interval [CI], 1.5-3.9; P = .0005). Rates of delayed endoscopic examinations were lower in patients with higher socioeconomic status (aOR = 0.77; 95% CI, 0.68-0.88). ICU admission rates were higher for weekend compared with weekday admissions (8% vs 6%, P = .004). The presence of a delayed endoscopic examination was associated with an increased length of stay of 1.3 days (95% CI, 1.2-1.4 days).

CONCLUSIONS

Weekend admissions for angiodysplasia were associated with higher odds of mortality, ICU admissions, higher rates of delayed endoscopic procedures, longer lengths of stay, and higher hospital charges.

摘要

背景与目的

胃肠道(GI)血管发育不良(GIAD)病变是整个胃肠道出血的一个重要原因,尤其在老年人中更为常见。本研究旨在确定 GIAD 患者的周末住院与平日住院相比,死亡率是否更高。

方法

我们使用 2000 年至 2011 年国家住院患者样本数据库进行了一项回顾性研究,包括国际疾病分类,第九版临床修订版(ICD-9-CM)用于胃肠道 GIAD 的代码(537.82 或 537.83)的住院患者。我们评估了延迟内镜检查(入院后 24 小时以上进行的检查)、重症监护病房(ICU)入院和住院死亡率的发生率。进行了双变量和多变量逻辑回归分析,以确定死亡率的危险因素。

结果

在 2000 年至 2011 年期间,有 85971 例 GIAD 出院患者,其中 69984 例(81%)为平日住院,15987 例(19%)为周末住院。与平日住院相比,周末住院的患者更有可能接受延迟内镜检查(35%比 26%,P≤0.0001)。周末住院患者的死亡率更高(2%比 1%,P=0.0002)。周末住院与住院患者死亡率相关的调整后优势比(aOR)升高(2.4;95%置信区间[CI],1.5-3.9;P=0.0005)。社会经济地位较高的患者,延迟内镜检查的比例较低(aOR=0.77;95%CI,0.68-0.88)。与平日住院相比,周末住院的 ICU 入院率更高(8%比 6%,P=0.004)。延迟内镜检查的存在与住院时间延长 1.3 天相关(95%CI,1.2-1.4 天)。

结论

周末因血管发育不良住院与死亡率、ICU 入院率、延迟内镜检查率、住院时间延长和住院费用增加的几率增加相关。

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