Ibrahim I A, Khalid S A, Omer S A, Adam S E
Department of Veterinary Medicine, Pharmacology and Toxicology, University of Khartoum, Sudan.
J Ethnopharmacol. 1992 Jan;35(3):267-73. doi: 10.1016/0378-8741(92)90024-l.
Brown Hisex chicks were fed diets containing 2% and 5% Azadirachta indica leaf from their 7th to 35th day of age. Thereafter, the chicks were fed control diet for 2 weeks. A depression in body weight gain and efficiency of feed utilization was observed in chicks fed A. indica leaf when compared with the control. The main clinicopathological changes were increases in lactic dehydrogenase, glutamic oxaloacetic transaminase and alkaline phosphatase activities and uric acid and bilirubin concentrations and decreases in the total protein levels in serum. Changes in the values of erythrocyte count, haemoglobin concentration, packed cell volume, mean corpuscular volume and mean corpuscular haemoglobin were remarkable and associated with yellow discoloration on the legs and combs and hepatonephropathy. Tissue recovery was incomplete 2 weeks after removal from the experimental diets.
棕色来亨鸡雏鸡从7日龄至35日龄饲喂含2%和5%印楝叶的日粮。此后，雏鸡饲喂对照日粮2周。与对照组相比，饲喂印楝叶的雏鸡体重增加和饲料利用率降低。主要的临床病理变化是血清中乳酸脱氢酶、谷草转氨酶和碱性磷酸酶活性以及尿酸和胆红素浓度升高，总蛋白水平降低。红细胞计数、血红蛋白浓度、血细胞比容、平均红细胞体积和平均红细胞血红蛋白值的变化显著，且与腿部和鸡冠发黄以及肝肾病变有关。从实验日粮中去除2周后，组织恢复不完全。
