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本文引用的文献
1
Characterization and partial purification of protein fatty acyltransferase activity from rat liver.
Biochim Biophys Acta. 2003 Nov 30;1635(1):10-9. doi: 10.1016/j.bbalip.2003.10.001.
2
Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs.
Biochem J. 2003 Jul 1;373(Pt 1):91-9. doi: 10.1042/BJ20021598.
3
Targeting RAS signalling pathways in cancer therapy.
Nat Rev Cancer. 2003 Jan;3(1):11-22. doi: 10.1038/nrc969.
4
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.
Hum Mol Genet. 2002 Nov 1;11(23):2815-28. doi: 10.1093/hmg/11.23.2815.
5
The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase.
J Cell Biol. 2002 Oct 14;159(1):23-8. doi: 10.1083/jcb.200206120. Epub 2002 Oct 7.
6
A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity.
Anal Biochem. 2002 Sep 1;308(1):160-7. doi: 10.1016/s0003-2697(02)00212-9.
7
Signal transduction--directed cancer treatments.
Annu Rev Pharmacol Toxicol. 2003;43:199-231. doi: 10.1146/annurev.pharmtox.43.100901.135813. Epub 2002 Jan 10.
8
Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.
J Biol Chem. 2002 Oct 25;277(43):41268-73. doi: 10.1074/jbc.M206573200. Epub 2002 Aug 21.
9
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway.
Mol Cell Biol. 2000 Apr;20(7):2475-87. doi: 10.1128/MCB.20.7.2475-2487.2000.
10
Caveolins, liquid-ordered domains, and signal transduction.
Mol Cell Biol. 1999 Nov;19(11):7289-304. doi: 10.1128/MCB.19.11.7289.
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