Short Matthew W, Vaughan Thomas K
Department of Family Practice, Bayne-Jones Army Community Hospital, Fort Polk, Louisiana, USA.
Cutis. 2004 Sep;74(3):185-8.
Systemic sequential therapy using cyclosporine and acitretin is a novel strategy that can provide quick resolution and maintenance in refractory cases of psoriasis. We describe the case of a patient with a psoriatic flare over 98% of his body, despite methotrexate therapy. Implementing sequential therapy with cyclosporine and acitretin maximized the benefit of each treatment and allowed for rapid improvement with minimal risk of toxicity.
使用环孢素和阿维A的系统性序贯疗法是一种新策略，可在银屑病难治性病例中实现快速缓解和维持疗效。我们描述了一例患者，尽管接受了甲氨蝶呤治疗，但全身98%以上出现银屑病发作。采用环孢素和阿维A的序贯疗法可使每种治疗的益处最大化，并能在毒性风险最小的情况下实现快速改善。
