银屑病的当前全身治疗方法：我们目前处于什么阶段？

Current systemic therapies for psoriasis: where are we now?

作者信息

Yamauchi Paul S, Rizk Dalia, Kormeili Tanya, Patnaik Rickie, Lowe Nicholas J

机构信息

Clinical Research Specialists, UCLA School of Medicine, 2001 Santa Monica Boulevard, Santa Monica, CA 90404, USA.

出版信息

J Am Acad Dermatol. 2003 Aug;49(2 Suppl):S66-77. doi: 10.1016/mjd.2003.550.

DOI:10.1016/mjd.2003.550

PMID:12894129

Abstract

Many systemic agents are used in the treatment of psoriasis. They provide good control of psoriasis in the majority of patients and have improved their life quality indices. Frequently, combination therapy is utilized to synergize the efficacy of these medications. Many dermatologists are hesitant in prescribing systemic agents because of their adverse effects. However, such potential toxicities arising from these medications can largely be avoided if proper patient selection and close monitoring are performed.

摘要

许多全身性药物被用于治疗银屑病。它们能使大多数患者的银屑病得到良好控制，并改善了他们的生活质量指标。通常，联合治疗被用于增强这些药物的疗效。许多皮肤科医生因全身性药物的不良反应而对其处方有所犹豫。然而，如果进行适当的患者选择和密切监测，这些药物产生的潜在毒性在很大程度上是可以避免的。