Worsley Keith J, Taylor Jonathan E, Tomaiuolo Francesco, Lerch Jason
Department of Mathematics and Statistics, McGill University, Montreal, Canada H3A 2K6.
Neuroimage. 2004;23 Suppl 1:S189-95. doi: 10.1016/j.neuroimage.2004.07.026.
We report new random field theory P values for peaks of canonical correlation SPMs for detecting multiple contrasts in a linear model for multivariate image data. This completes results for all types of univariate and multivariate image data analysis. All other known univariate and multivariate random field theory results are now special cases, so these new results present a true unification of all currently known results. As an illustration, we use these results in a deformation-based morphometry (DBM) analysis to look for regions of the brain where vector deformations of nonmissile trauma patients are related to several verbal memory scores, to detect regions of changes in anatomical effective connectivity between the trauma patients and a group of age- and sex-matched controls, and to look for anatomical connectivity in cortical thickness.
我们报告了用于检测多元图像数据线性模型中多个对比的典型相关统计参数映射(SPM)峰值的新随机场理论P值。这完善了所有类型单变量和多变量图像数据分析的结果。所有其他已知的单变量和多变量随机场理论结果现在都是特殊情况,因此这些新结果真正统一了所有当前已知的结果。作为示例,我们将这些结果用于基于变形的形态测量(DBM)分析,以寻找非导弹创伤患者的向量变形与多个言语记忆分数相关的脑区,检测创伤患者与一组年龄和性别匹配的对照组之间解剖学有效连接性变化的区域,并寻找皮质厚度的解剖学连接性。