Liu Fang-ying, Zhang Xue-lin, Shang Jian-biao, Wang Quan-shi
Diagnostic Imaging Centre, Southern Medical University, Guangzhou 510515, China.
Di Yi Jun Yi Da Xue Xue Bao. 2004 Oct;24(10):1186-7, 1191.
To evaluate the diagnostic value of (18)F-FDG positron emission tomography (PET) in mediastinal staging of lung cancer.
A retrospective analysis of mediastinal staging was carried out in 41 cases of lung cancer by comparing the preoperative mediastinal FDG PET and CT findings with the pathological results.
According to the pathological results, 18 patients had mediastinal metastasis, 17 of whom were correctly identified by FDG PET, and 10 by CT. Of the other 23 patients without mediastinal metastasis pathologically, 22 were correctly diagnosed by FDG PET and 20 by CT. The sensitivity and accuracy for diagnosis of regional mediastinal lymph node metastasis with FDG PET were 94.4% and 95.1%, obviously higher than those of CT (55.6% and 73.2%, P<0.05).
FDG PET is a better alternative for mediastinal staging of lung cancer, specially for identification of small lymph node metastasis escaping detection by CT, to provide important evidence for clinical staging and treatment planning of lung cancer.
评估（18）F-FDG正电子发射断层显像（PET）在肺癌纵隔分期中的诊断价值。
对41例肺癌患者的纵隔分期进行回顾性分析，将术前纵隔FDG PET和CT检查结果与病理结果进行比较。
根据病理结果，18例有纵隔转移，其中17例经FDG PET正确诊断，10例经CT正确诊断。另外23例病理上无纵隔转移的患者中，22例经FDG PET正确诊断，20例经CT正确诊断。FDG PET诊断纵隔区域淋巴结转移的敏感性和准确性分别为94.4%和95.1%，明显高于CT（55.6%和73.2%，P<0.05）。
FDG PET是肺癌纵隔分期的更好选择，尤其对于识别CT难以检测到的小淋巴结转移，可为肺癌的临床分期和治疗方案提供重要依据。
