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球形幽门螺杆菌细胞中缺乏阶段特异性蛋白。

Lack of stage-specific proteins in coccoid Helicobacter pylori cells.

作者信息

Bumann Dirk, Habibi Hajar, Kan Biao, Schmid Monika, Goosmann Christian, Brinkmann Volker, Meyer Thomas F, Jungblut Peter R

机构信息

Department of Molecular Biology, Max-Planck-Institute for Infection Biology, Berlin, Germany.

出版信息

Infect Immun. 2004 Nov;72(11):6738-42. doi: 10.1128/IAI.72.11.6738-6742.2004.

Abstract

Helicobacter pylori exists in two distinct forms, rod shaped or coccoid, in stomachs of infected patients. Based on in vitro proteome comparisons, there are no detectable coccoid-specific proteins, which argues against the specific adaptation of coccoid Helicobacter to distinct biological functions, such as enhanced persistence or transmission to other hosts.

摘要

幽门螺杆菌在受感染患者的胃中以两种不同形态存在,即杆状或球状。基于体外蛋白质组比较,未检测到球状特异性蛋白,这表明球状幽门螺杆菌并无针对不同生物学功能(如增强的持久性或传播至其他宿主)的特异性适应。

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