Baklan Zvonko, Gorisek Jelka Rebersek, Poljak Mario, Pisec Andrej
Department of Infectious Diseases, Maribor Teaching Hospital, Maribor, Slovenia.
Wien Klin Wochenschr. 2004;116 Suppl 2:5-7.
The prevalence of human immunodeficiency virus (HIV) infection and hepatitis B, C, and G virus infections was determined in a selected group of 40 intravenous drug addicts on methadone maintenance treatment. No drug addict was infected with HIV. Seven drug addicts (17.5%) had serologic markers of hepatitis B infection but only one among them (2.5%) exhibited signs of active infection. 16 drug addicts (40%) had serologic markers of hepatitis C infection and 13 (32.5%) of them had an active infection with positive viral tests. 22 addicts (55%) had signs of hepatitis G infection, 9 (22.5%) of them had signs of active infection and 13 (32.5%) had signs of past infection. Addicts infected with the hepatitis B and C viruses were older and had also been taking drugs longer than those who were not infected with these two viruses. The proportion of those susceptible to infection with hepatitis B (70%) is high, reflecting a low prevalence of this disease and at the same time revealing the failure of preventive measures and the unacceptably low vaccination rate.
在一组接受美沙酮维持治疗的40名静脉注射吸毒者中,测定了人类免疫缺陷病毒(HIV)感染以及乙型、丙型和庚型肝炎病毒感染的流行情况。没有吸毒者感染HIV。7名吸毒者(17.5%)有乙型肝炎感染的血清学标志物,但其中只有1名(2.5%)表现出活动性感染迹象。16名吸毒者(40%)有丙型肝炎感染的血清学标志物,其中13名(32.5%)病毒检测呈阳性,有活动性感染。22名吸毒者(55%)有庚型肝炎感染迹象,其中9名(22.5%)有活动性感染迹象,13名(32.5%)有既往感染迹象。感染乙型和丙型肝炎病毒的吸毒者比未感染这两种病毒的吸毒者年龄更大,吸毒时间也更长。对乙型肝炎易感者的比例(70%)很高,这反映出该病的低流行率,同时也表明预防措施失败,疫苗接种率低得令人无法接受。