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孕期合并母胎手术后的生殖结局。

Reproductive outcomes after pregnancy complicated by maternal-fetal surgery.

作者信息

Wilson R Douglas, Johnson Mark P, Flake Alan W, Crombleholme Timothy M, Hedrick Holly L, Wilson Jordan, Adzick N Scott

机构信息

Pediatric Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

出版信息

Am J Obstet Gynecol. 2004 Oct;191(4):1430-6. doi: 10.1016/j.ajog.2004.05.054.

Abstract

OBJECTIVE

The reproductive outcomes for women after the pregnancy complicated by maternal-fetal surgery were evaluated to obtain evidence-based information for prenatal risk counseling.

STUDY DESIGN

The retrospective review identified 83 women with maternal-fetal surgery from a single institution (1996-2002). These women were sent a consent form and a questionnaire to document postoperative problems, fertility, obstetric outcomes, and psychosocial concerns in pregnancy after the index fetal therapy. Institutional Review Board approval was obtained from Committee for Protection of Human Subjects.

RESULTS

The total return rate was 55 (66%). The pregnancy rate was 62% (18% spontaneous abortion, 24% preterm delivery, and 58% term delivery). Complications were reported in 12 of 34 pregnancies (35%), including uterine dehiscence/rupture (12%/6%), cesarean hysterectomy (3%), and antepartum hemorrhage requiring transfusion (9%).

CONCLUSION

The reproductive outcome of uterine dehiscence, rupture, and hysterectomy was 12%, 6%, and 3%, respectively, after a pregnancy complicated by maternal-fetal surgery. The uterine rupture rate is similar to the rupture rate after "classical" cesarean section (4%-9%).

摘要

目的

评估孕期合并母胎手术的女性的生殖结局,以获取用于产前风险咨询的循证信息。

研究设计

通过回顾性研究,从单一机构(1996 - 2002年)中确定了83例接受母胎手术的女性。向这些女性发送了一份同意书和一份问卷,以记录术后问题、生育能力、产科结局以及首次胎儿治疗后妊娠期间的心理社会问题。获得了人类受试者保护委员会的机构审查委员会批准。

结果

总回复率为55例(66%)。妊娠率为62%(自然流产18%,早产24%,足月分娩58%)。34例妊娠中有12例(35%)报告有并发症,包括子宫裂开/破裂(12%/6%)、剖宫产子宫切除术(3%)以及需要输血的产前出血(9%)。

结论

孕期合并母胎手术的女性,子宫裂开、破裂及子宫切除术的生殖结局分别为12%、6%和3%。子宫破裂率与“经典”剖宫产术后的破裂率(4% - 9%)相似。

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