Ukponmwan C U, Atamah A
University of Benin Teaching Hospital, P.O. Box 7139, Benin City, Edo State, Nigeria.
East Afr Med J. 2004 May;81(5):254-7. doi: 10.4314/eamj.v81i5.9169.
To determine the mode of presentation and degree of visual impairment of retinitis pigmentosa in Nigerians.
A prospective, non-comparative study.
University of Benin Teaching Hospital, Benin City, Nigeria.
Thirty Nigerian patients with a diagnosis of retinitis pigmentosa who presented at the Eye Clinic of the Ophthalmology Department of the University of Benin, Teaching Hospital, Benin City, Nigeria over a three year period (July 1997-June 2000) were included in the study. The clinical features and mode of presentation were noted. The examination included visual acuity, slit lamp examination and fundoscopy.
Presenting symptoms and signs, visual acuity.
The degree of visual impairment and clinical features in thirty Nigerians with retinitis pigmentosa seen at the University of Benin Teaching Hospital, Benin City, Nigeria were studied. There were twenty males and ten females. The age range was 14 to 71 years (mean 36.7 years +/- 14.8 years). Fifteen patients (50%) had visual acuity of less than 3/60 while only seven (23.3%) had visual acuity of 6/12 or better. The commonest mode of presentation was poor vision in 90% of the patients followed by night blindness in 56.7%. Others were headaches, flashes of light and floaters.
The degree of visual loss in Nigerians with retinitis pigmentosa is severe and may be related to the long duration of the disease and age of the patients at presentation. Health education of the public and patients about the need for early presentation to hospital and the use of vitamin A and carbonic anhydrase inhibitors are recommended.
确定尼日利亚视网膜色素变性患者的临床表现模式及视力损害程度。
前瞻性非对照研究。
尼日利亚贝宁城贝宁大学教学医院。
在三年期间(1997年7月至2000年6月)就诊于尼日利亚贝宁城贝宁大学教学医院眼科门诊、被诊断为视网膜色素变性的30名尼日利亚患者纳入本研究。记录其临床特征及临床表现模式。检查包括视力、裂隙灯检查及眼底镜检查。
临床表现症状及体征、视力。
对在尼日利亚贝宁城贝宁大学教学医院就诊的30名视网膜色素变性尼日利亚患者的视力损害程度及临床特征进行了研究。其中男性20例,女性10例。年龄范围为14至71岁(平均36.7岁±14.8岁)。15例患者(50%)视力低于3/60,而只有7例(23.3%)视力为6/12或更好。最常见的临床表现模式是90%的患者视力差,其次是56.7%的患者有夜盲症。其他症状为头痛、闪光及飞蚊症。
尼日利亚视网膜色素变性患者的视力丧失程度严重,可能与疾病持续时间长及就诊时患者年龄有关。建议对公众及患者进行健康教育,告知其尽早到医院就诊的必要性以及维生素A和碳酸酐酶抑制剂的使用。