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鼻息肉在慢性鼻-鼻窦炎中的意义:症状与手术疗效

Significance of nasal polyps in chronic rhinosinusitis: symptoms and surgical outcomes.

作者信息

Deal R Tyson, Kountakis Stilianos E

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical College of Georgia, Augusta, GA 30912, USA.

出版信息

Laryngoscope. 2004 Nov;114(11):1932-5. doi: 10.1097/01.mlg.0000147922.12228.1f.

Abstract

PURPOSE

To demonstrate the significance of nasal polyps on the symptoms of chronic rhinosinusitis (CRS) and their influence on surgical outcomes.

METHODS

Retrospective analysis of prospectively collected data comparing two groups of patients diagnosed with CRS with and without nasal polyps that underwent surgical management with a minimum 1-year follow-up period. Subjective scoring was performed using the Sino-Nasal Outcome Test (SNOT-20) questionnaire. Computed tomography (CT) scans were compared using the Lund-Mackay scoring system. The two groups were analyzed for the need of revision surgery.

RESULTS

Two hundred one patients underwent surgical management of CRS over a 3-year period. One hundred four were male, 97 were female, and the average age was 49 (range 18-80) years. Polyps were present in 78 patients with CRS, whereas 123 patients did not have polyps. The average CT score was 18 for the polyp group and 9.5 for the patients without polyps (P = .0000). Nonpolyp group SNOT-20 scores were 26.5 preoperatively with improvement to 5.1 at 6 months and 5.0 at 12 months postoperatively (85% improvement). Polyp group SNOT-20 preoperative scores averaged 32.2 with improvement to 9.2 at 6 months and 9.1 at 12 months postoperatively (81% improvement, P = .003). Nine patients required revision surgery (4.5%), eight (10%) who had polyps and one (0.8%) who did not (P = .002).

CONCLUSION

The presence of nasal polyps has a significant negative impact on patients with CRS. Patients with nasal polyps have more severe symptoms with less improvement after operative intervention, higher CT scores at presentation, and a significantly higher need for revision surgery.

摘要

目的

阐述鼻息肉对慢性鼻-鼻窦炎(CRS)症状的影响及其对手术效果的作用。

方法

对前瞻性收集的数据进行回顾性分析,比较两组诊断为CRS且有或无鼻息肉的患者,这些患者均接受了至少1年随访期的手术治疗。采用鼻-鼻窦结局测试(SNOT-20)问卷进行主观评分。使用Lund-Mackay评分系统比较计算机断层扫描(CT)结果。分析两组患者再次手术的必要性。

结果

在3年期间,201例患者接受了CRS手术治疗。其中男性104例,女性97例,平均年龄49岁(范围18 - 80岁)。78例CRS患者有鼻息肉,123例患者无鼻息肉。息肉组的平均CT评分为18分,无息肉患者为9.5分(P = 0.0000)。非息肉组术前SNOT-20评分为26.5分,术后6个月改善至5.1分,术后12个月为5.0分(改善85%)。息肉组术前SNOT-20评分平均为32.2分,术后6个月改善至9.2分,术后12个月为9.1分(改善81%,P = 0.003)。9例患者需要再次手术(4.5%),其中8例(10%)有鼻息肉,1例(0.8%)无鼻息肉(P = 0.002)。

结论

鼻息肉的存在对CRS患者有显著负面影响。有鼻息肉的患者症状更严重,手术干预后改善较少,就诊时CT评分更高,再次手术的需求显著更高。

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