Hopkins C, Browne J P, Slack R, Lund V, Topham J, Reeves B, Copley L, Brown P, van der Meulen J
Clinical Effectiveness Unit, Royal College of Surgeons of England, London.
Clin Otolaryngol. 2006 Oct;31(5):390-8. doi: 10.1111/j.1749-4486.2006.01275.x.
This study summarises the results of a National Audit of sino-nasal surgery carried out in England and Wales. It describes patient and operative characteristics as well as patient outcomes up to 36 months after surgery.
Prospective cohort study.
NHS hospitals in England and Wales.
Consecutive patients undergoing surgery for nasal polyposis and/or chronic rhinosinusitis.
The total score derived from a 22-item version of the Sino-Nasal Outcome Test (SNOT-22). Lower scores represent better health-related quality of life.
A total of 3128 consecutive patients at 87 NHS hospitals were enrolled. There is a large improvement in SNOT-22 scores from the pre-operative period (mean = 42.0) to 3 months after surgery (mean = 25.5). The scores for patients undergoing nasal polypectomy improved from 41.0 before surgery to 23.1 at 3 months after surgery, while the scores for patients undergoing surgery for chronic rhinosinusitis alone improved from 44.2 to 31.2. The SNOT-22 scores reported at 12 and 36 months after surgery were similar to those reported at 3 months. Excessive bleeding occurred in 5% of patients during the operation and in 1% of patients after the operation. Intra-orbital complications were reported in 0.2%. Of those patients undergoing primary surgery for bilateral grade I or II polyposis, 18% had not received a pre-operative course of steroid treatment. At the 36-month follow-up, 11.4% of patients had undergone revision surgery.
The audit confirms that sino-nasal surgery is generally safe and effective. There is some evidence that patient selection for surgery could be improved.
本研究总结了在英格兰和威尔士开展的一项全国性鼻窦手术审计的结果。它描述了患者和手术特征以及术后36个月内的患者结局。
前瞻性队列研究。
英格兰和威尔士的国民保健服务(NHS)医院。
连续接受鼻息肉和/或慢性鼻窦炎手术的患者。
源自22项鼻窦结局测试(SNOT - 22)版本的总分。分数越低代表与健康相关的生活质量越好。
87家NHS医院的3128名连续患者入组。从术前时期(平均 = 42.0)到术后3个月(平均 = 25.5),SNOT - 22分数有大幅改善。接受鼻息肉切除术的患者分数从术前的41.0提高到术后3个月的23.1,而仅接受慢性鼻窦炎手术的患者分数从44.2提高到31.2。术后12个月和36个月报告的SNOT - 22分数与术后3个月报告的分数相似。5%的患者在手术期间出现大出血,1%的患者在术后出现大出血。眶内并发症报告率为0.2%。在接受双侧I级或II级息肉初次手术的患者中,18%未接受术前类固醇治疗疗程。在36个月的随访中,11.4%的患者接受了翻修手术。
该审计证实鼻窦手术总体上是安全有效的。有一些证据表明手术患者的选择可以改进。