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同步双原发恶性肿瘤:石棉暴露诱发的肺腺癌和恶性星形细胞瘤。

Synchronous double malignancy: adenocarcinoma of lung and malignant astrocytoma induced by asbestos exposure.

作者信息

Kishimoto T, Hashimoto H, Ono T, Okada K

机构信息

Department of Clinical Investigation, Kure Kyosai Hospital, Nishichuo Kure, Japan.

出版信息

Cancer Invest. 1992;10(2):129-33. doi: 10.3109/07357909209032773.

Abstract

A 54-year-old male died of cerebellar herniation induced by brain tumor. Radiological examination of this case showed two separate tumorous lesions in the brain and lung. Autopsy proved malignant astrocytoma in the brain and coincidental alveolar cell carcinoma in the lung. He had a history of asbestos exposure for 8 years doing piping work in a shipyard. Furthermore, we detected a large number of asbestos bodies in the lung and one asbestos body in the brain. Therefore, this rare case of double cancer (malignant astrocytoma and lung cancer) might have been induced by asbestos exposure.

摘要

一名54岁男性死于脑肿瘤引起的小脑疝。该病例的影像学检查显示脑和肺中有两个独立的肿瘤性病变。尸检证实脑部为恶性星形细胞瘤,肺部为巧合的肺泡细胞癌。他有在造船厂从事管道工作8年的石棉接触史。此外,我们在肺部检测到大量石棉小体,在脑部检测到一个石棉小体。因此,这种罕见的双癌(恶性星形细胞瘤和肺癌)病例可能是由石棉接触引起的。

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