Gierek-Lapińska Ariadna, Leszczyński Rafał, Wróbel Andrzej
Kliniki Okulistyki Slaskiej Akademii Medycznej w Katowicach.
Klin Oczna. 2004;106(1-2 Suppl):168-9.
The purpose of the paper was to examine the efficacy of non-penetrating deep sclerectomy (NPDS) with sodium hyaluronate implants and mitomycin C in the treatment of advanced cases of open angle glaucoma.
Thirty-five eyes of 35 patients with medically uncontrolled advanced open angle glaucoma were retrospectively analyzed. Visual acuity and intraocular pressure measurement were performed before and after surgery at 1 and 7 days and 1, 6 and 12 months. Visual field was analyzed before and 12 months after surgery.
The mean preoperative intraocular pressure was 27+/-3.1 mm Hg and 18.1+/-1.5 at 12 month after surgery (p<0.05). Visual acuity decreased more than two rows on Snellen chart in 4 patients. Visual field analysis shows mean defect MD--17+/-5.2 before surgery and 20.1+/-6.2 after 12 month of follow up (p>0.05). Complete success rate defined as an IOP lower than 21 mmHg without medications was 51%. In 3 eyes we performed needling and in 8 goniopuncture. Postoperative complications included hyphaema in 3 eyes, choroidal detachment in 1 eye, bleb fibrosis in 2 eyes.
本文旨在探讨透明质酸钠植入联合丝裂霉素C的非穿透性深层巩膜切除术（NPDS）治疗晚期开角型青光眼的疗效。
回顾性分析35例药物治疗无法控制的晚期开角型青光眼患者的35只眼。在手术前、术后1天和7天以及1、6和12个月时进行视力和眼压测量。在手术前和术后12个月进行视野分析。
术前平均眼压为27±3.1 mmHg，术后12个月为18.1±1.5 mmHg（p<0.05）。4例患者的视力在斯内伦视力表上下降超过两行。视野分析显示，术前平均缺损MD为-17±5.2，随访12个月后为20.1±6.2（p>0.05）。定义为无需药物治疗眼压低于21 mmHg的完全成功率为51%。3只眼进行了针刺治疗，8只眼进行了房角穿刺术。术后并发症包括3只眼发生前房积血，1只眼发生脉络膜脱离，2只眼发生滤过泡纤维化。
