胀果甘草对四氧嘧啶诱导的糖尿病大鼠组织的抗氧化作用。
Antioxidant effect of Boerhavia diffusa L. in tissues of alloxan induced diabetic rats.
作者信息
Satheesh M Amarnath, Pari L
机构信息
Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar 608 002, India.
出版信息
Indian J Exp Biol. 2004 Oct;42(10):989-92.
Administration of B. diffusa leaf extract (BLEt; 200 mg/kg) for 4 weeks resulted in a significant reduction in thiobarbutric acid reactive substances and hydroperoxides, with a significant increase in reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase and glutathione--S-transferase in liver and kidney of alloxan induced diabetic rats. The results suggest that BLEt has remarkable antidiabetic activity and can improve antioxidant status in alloxan induced diabetic rats.
给予白花蛇舌草叶提取物（BLEt；200毫克/千克）4周，可使四氧嘧啶诱导的糖尿病大鼠肝脏和肾脏中的硫代巴比妥酸反应性物质和氢过氧化物显著减少，同时还原型谷胱甘肽、超氧化物歧化酶、过氧化氢酶、谷胱甘肽过氧化物酶和谷胱甘肽-S-转移酶显著增加。结果表明，BLEt具有显著的抗糖尿病活性，并可改善四氧嘧啶诱导的糖尿病大鼠的抗氧化状态。
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