Gordon Paul H, Miller Robert G, Moore Dan H
Eleanor and Lou Gehrig MDA/ALS Research Center, Neurological Institute, New York, NY 10032, USA.
Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Sep;5 Suppl 1:90-3. doi: 10.1080/17434470410019906.
The ALSFRS-R is an attractive primary outcome measure in clinical trials of ALS because it is validated, easy to administer, minimizes dropout, reduces cost, and correlates with survival. Unlike the other standard outcome measures currently employed, the ALSFRS-R is also a measure of global function.