通过在硝基乙烷中进行CBS还原对烯丙基甲醇进行对映选择性合成：反应性和对映选择性的显著溶剂效应。
Enantioselective synthesis of allenyl carbinols by the CBS reduction in nitroethane: dramatic solvent effect for reactivity and enantioselectivity.
作者信息
Yu Chan-Mo, Kim Chunsan, Kweon Jae-Hong
机构信息
Department of Chemistry and Lab for Metal-Catalysed Reactions, Sungkyunkwan University, Suwon, 440-746, Korea.
出版信息
Chem Commun (Camb). 2004 Nov 7(21):2494-5. doi: 10.1039/b407387h. Epub 2004 Sep 13.
DOI:10.1039/b407387h
PMID:15514832
Abstract
Dramatic solvent effect of nitroethane was observed in the catalytic asymmetric reductions of allenyl ketones and alpha,beta-ynones using the oxazaborolidine cayalyst to yield the corresponding alcohols in high levels of enantioselectivity.
摘要
在使用恶唑硼烷催化剂对烯丙基酮和α,β-炔酮进行催化不对称还原反应中，观察到硝基乙烷具有显著的溶剂效应，能以高对映选择性生成相应的醇。
Zotero 插件