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土耳其西部农村地区白塞病的患病率:初步报告。

Prevalence of Behçet's disease in rural western Turkey: a preliminary report.

作者信息

Cakir N, Dervis E, Benian O, Pamuk O N, Sonmezates N, Rahimoglu R, Tuna S, Cetin T, Sarikaya Y

机构信息

Department of Rheumatology, The University of Trakya, Edirne, Turkey.

出版信息

Clin Exp Rheumatol. 2004 Jul-Aug;22(4 Suppl 34):S53-5.

Abstract

OBJECTIVES

To study the prevalence of Behçet's disease (BD) in a rural area of Western Turkey.

METHODS

This study was conducted in seven villages in the rural Havsa region which has a total population of 5727. The physicians and medical students visited every household and distributed a questionnaire on the symptoms of rheumatic disorders. One of the questions was whether they had ever suffered from mouth ulcers. If the response was affirmative the proband was examined by a rheumatologist and a dermatologist for other symptoms. The individuals with true aphthous ulcerations had pathergy tests and were invited to the hospital for ophtalmic examinations.

RESULTS

Of the 5203 individuals who participated in this survey, 4861 were 10 years or older. 124 out of 190 individuals who responded positively to the question regarding the presence of mouth ulcers had true aphthous ulcerations. 115/124 underwent a pathergy test and 4 showed positive reactions without any other stigmata of BD, except for folliculitis in one. Among the individuals with a negative pathergy test, 2 had acneiform skin lesions and 1 a genital ulcer. No individual exhibited any ocular symptoms or findings characteristic for BD. Only 1 person with aphthous ulceration, folliculitis and a positive pathergy test was considered to have BD.

CONCLUSION

In this survey, the prevalence of BD was found to be 2: 10,000 (95% confidence interval 0 to 4.3: 10,000). This figure is lower than what has been reported in four previous studies from different regions in Turkey. This finding might be due to ethnic distribution and geographical differences.

摘要

目的

研究土耳其西部农村地区白塞病(BD)的患病率。

方法

本研究在农村哈夫萨地区的七个村庄进行,该地区总人口为5727人。医生和医学生走访了每户家庭,并发放了一份关于风湿性疾病症状的问卷。其中一个问题是他们是否曾患口腔溃疡。如果回答是肯定的,先证者会由风湿病学家和皮肤科医生检查是否有其他症状。患有真正阿弗他溃疡的个体进行了针刺反应试验,并被邀请到医院进行眼科检查。

结果

在参与本次调查的5203人中,4861人年龄在10岁及以上。在对口腔溃疡问题回答为阳性的190人中,124人患有真正的阿弗他溃疡。115/124人进行了针刺反应试验,4人呈阳性反应,除1人有毛囊炎外,无其他白塞病体征。在针刺反应试验阴性的个体中,2人有痤疮样皮肤损害,1人有生殖器溃疡。没有个体表现出任何白塞病特征性的眼部症状或体征。只有1例患有阿弗他溃疡、毛囊炎且针刺反应试验呈阳性的个体被认为患有白塞病。

结论

在本次调查中,白塞病的患病率为2:10000(95%置信区间0至4.3:10000)。这一数字低于土耳其不同地区此前四项研究报告的结果。这一发现可能是由于种族分布和地理差异。

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