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[乳酸菌对人体不同腔道上皮的黏附作用]

[Adhesion of lactic acid bacteria to epithelium of different cavities of the human organism].

作者信息

Kovalenko N K, Podgorskiĭ V S, Kasumova S A

出版信息

Mikrobiol Z. 2004 Jul-Aug;66(4):62-8.

PMID:15515903
Abstract

During investigation of adhesive properties of lactic acid bacteria it was found out that 11 strains adhered to buccal intestinal and vaginal epithelium of human. The highest adhesive activity was detected in enterococci (adhesive index 7.75-14.26), lower one--in streptococci (6.40-9.16). In lactobacilli adhesive properties manifested in different ways: Lactobacillus acidophilus strains adhered more often to buccal epithelium (2.58-4.60) and rarely--to intestinal and vaginal. L. plantarum manifested high adhesive activity (8.03 -9.69) to buccal epithelium and lower one--to the rest of epithelium types. Monosaccharide composition of glycocalix of 6 strains of lactic acid bacteria was studied to understand the adhesion mechanism. It was shown that surface structures of this microorganism interact with plant lectins, specific to certain monosaccharides.

摘要

在对乳酸菌黏附特性的研究中发现,有11株菌能黏附于人的颊黏膜、肠道和阴道上皮。肠球菌的黏附活性最高(黏附指数为7.75 - 14.26),链球菌的黏附活性较低(6.40 - 9.16)。乳酸菌的黏附特性表现各异:嗜酸乳杆菌菌株更常黏附于颊黏膜上皮(2.58 - 4.60),很少黏附于肠道和阴道上皮。植物乳杆菌对颊黏膜上皮表现出较高的黏附活性(8.03 - 9.69),对其他类型上皮的黏附活性较低。研究了6株乳酸菌糖萼的单糖组成,以了解其黏附机制。结果表明,这种微生物的表面结构与特定单糖的植物凝集素相互作用。

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