Garmasheva I L, Kovalenko N K
Mikrobiol Z. 2005 Jul-Aug;67(4):68-84.
Current status of the question concerning the study of lactic acid bacteria adhesion process is presented in the review. Lactic acid bacteria colonization capacity allows them to form monolayers, to join the mucosal microbiota, to become a component of ecological barrier, which protects an organism from penetration of pathogens. The available methods of investigation of adhesive properties such as microbiological, light and electron microscopy, biophysical, mathematical and others are presented in detail. The works concerning lactic acid bacteria adhesines nature and factors that influence the exhibition of adhesion have been analyzed. Studies concerning the mechanisms responsible for attachment of cells of lactic acid bacteria to the surface of different types of epithelium and substances that are products of endothelium secretion are analyzed. Questions on adhesion specificity and factors that inhibit its exhibition are considered. The chart of current concept of the adhesive process and factors that reciprocally affect the exhibition of lactic acid bacteria adhesion properties is developed and presented by the authors.
这篇综述介绍了乳酸菌黏附过程研究的当前状况。乳酸菌的定殖能力使其能够形成单层，加入黏膜微生物群，成为生态屏障的一个组成部分，从而保护机体免受病原体的侵入。详细介绍了现有的黏附特性研究方法，如微生物学、光学和电子显微镜、生物物理、数学等方法。分析了有关乳酸菌黏附素性质以及影响黏附表现的因素的研究。分析了有关乳酸菌细胞附着于不同类型上皮表面的机制以及内皮细胞分泌产物的研究。考虑了黏附特异性问题以及抑制其表现的因素。作者绘制并展示了黏附过程的当前概念图以及相互影响乳酸菌黏附特性表现的因素。
