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[电磁辐射的射频对酵母对杀真菌抗生素敏感性的影响]

[Effect of radiofrequency of electromagnetic radiation on yeast sensitivity to fungicide antibiotics].

作者信息

Voĭchuk S I, Gromozova E N

出版信息

Mikrobiol Z. 2004 Jul-Aug;66(4):69-77.

PMID:15515904
Abstract

Saccharomyces cerevisiae UCM Y-517, Candida utilis UCM Y-961 and Schizosaccharomyces pombe UCM Y-94T have been studied for their sensitivity to fungicide antibiotics under the effect of electromagnetic radiation (40.68 MHz, 15 and 30 W). Yeast sensitivity to nystatin, amphotericin B, klotrimazol, itrakonazol, flukonazol as well as the effects arising as a result of the effect of radiofrequency radiation are characterized by species specificity. Irradiation did not exert statistically reliable effect on S. cerevisiae and S. pombe sensitivity to fungicide antibiotics. The increase of resistance of C. utilis to antibiotics (growth delay zones were absent in 70-90% of experiments) in the case of preliminary irradiation of this strain was stated. Separate preliminary irradiation of antibiotics did not result in the change of their antifungal activity. The arising effects were noticed to depend on the radiation power. Possible reasons of species specificity in sensing electromagnetic radiation are considered.

摘要

已对酿酒酵母UCM Y - 517、产朊假丝酵母UCM Y - 961和粟酒裂殖酵母UCM Y - 94T在电磁辐射(40.68 MHz,15和30 W)作用下对杀真菌抗生素的敏感性进行了研究。酵母对制霉菌素、两性霉素B、克霉唑、伊曲康唑、氟康唑的敏感性以及射频辐射作用产生的影响具有物种特异性。辐照对酿酒酵母和粟酒裂殖酵母对杀真菌抗生素的敏感性没有统计学上可靠的影响。在对该菌株进行预辐照的情况下,产朊假丝酵母对抗生素的抗性增加(在70 - 90%的实验中没有生长延迟区)。单独对抗生素进行预辐照不会导致其抗真菌活性的改变。注意到产生的影响取决于辐射功率。考虑了在感知电磁辐射中物种特异性的可能原因。

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