2004年HIV-1耐药性突变的更新情况。 - Suppr

Update of the drug resistance mutations in HIV-1: 2004.

作者信息

Johnson Victoria A, Brun-Vézinet Francoise, Clotet Bonaventura, Conway Brian, D'Aquila Richard T, Demeter Lisa M, Kuritzkes Daniel R, Pillay Deenan, Schapiro Jonathan M, Telenti Amalio, Richman Douglas D

机构信息

Veterans Affairs Medical Center, Birmingham, AL, USA.

出版信息

Top HIV Med. 2004 Oct-Nov;12(4):119-24.

PMID:15516709

Abstract

摘要

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Update of the drug resistance mutations in HIV-1: 2004.2004年HIV-1耐药性突变的更新情况。

Top HIV Med. 2004 Oct-Nov;12(4):119-24.

Highly active antiretroviral therapy failure and protease and reverse transcriptase human immunodeficiency virus type 1 gene mutations.高效抗逆转录病毒疗法失败与蛋白酶及1型人类免疫缺陷病毒逆转录酶基因突变

J Infect Dis. 1999 Aug;180(2):568-71. doi: 10.1086/314909.

Prevalence of drug resistance and newly recognised treatment-related substitutions in the HIV-1 reverse transcriptase and protease genes from HIV-positive patients naïve for anti-retrovirals.未接受过抗逆转录病毒治疗的HIV阳性患者中，HIV-1逆转录酶和蛋白酶基因的耐药性流行情况及新发现的与治疗相关的替代情况。

Clin Microbiol Infect. 2004 Sep;10(9):826-30. doi: 10.1111/j.1469-0691.2004.00938.x.

Cross-resistance within the protease inhibitor class.蛋白酶抑制剂类药物的交叉耐药性。

Antivir Ther. 2001;6 Suppl 2:29-36.

Prevalence of drug resistance mutations in Spain among both naive and pretreated patients.西班牙初治和经治患者中耐药突变的流行情况。

Antivir Ther. 1999;4 Suppl 3:57-63.

Profile of drug resistance mutations among HIV-1-infected Tunisian subjects failing antiretroviral therapy.接受抗逆转录病毒治疗失败的突尼斯HIV-1感染者的耐药突变情况

Arch Virol. 2008;153(6):1103-8. doi: 10.1007/s00705-008-0104-z. Epub 2008 May 16.

Frequency of protease and reverse transcriptase drug resistance mutations in naïve HIV-infected patients.初治HIV感染患者中蛋白酶和逆转录酶耐药突变的频率

Arch Med Res. 2006 Nov;37(8):1022-7. doi: 10.1016/j.arcmed.2006.05.014.

Long-term analysis of the resistance development in HIV-1 positive patients treated with protease and reverse transcriptase inhibitors: correlation of the genotype and disease progression.对接受蛋白酶和逆转录酶抑制剂治疗的HIV-1阳性患者耐药性发展的长期分析：基因型与疾病进展的相关性。

Acta Virol. 2005;49(1):29-36.

Polymorphism in HIV-1 non-subtype B protease and reverse transcriptase and its potential impact on drug susceptibility and drug resistance evolution.HIV-1非B亚型蛋白酶和逆转录酶的多态性及其对药物敏感性和耐药性演变的潜在影响。

AIDS Rev. 2003 Jan-Mar;5(1):25-35.

Primary drug resistance in antiretroviral-naïve injection drug users.初治注射吸毒者的原发性耐药。

Int J Infect Dis. 2009 Sep;13(5):577-83. doi: 10.1016/j.ijid.2008.08.028. Epub 2008 Dec 25.

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A decade of viral mutations and associated drug resistance in a population of HIV-1+ Puerto Ricans: 2002-2011.2002 - 2011年波多黎各艾滋病毒-1感染者群体中十年的病毒突变及相关耐药性情况

PLoS One. 2017 May 11;12(5):e0177452. doi: 10.1371/journal.pone.0177452. eCollection 2017.

Assessment of the effect of antiretroviral therapy on renal and liver functions among HIV-infected patients: a retrospective study.评估抗逆转录病毒疗法对HIV感染患者肾功能和肝功能的影响：一项回顾性研究。

HIV AIDS (Auckl). 2016 Dec 22;9:1-7. doi: 10.2147/HIV.S120979. eCollection 2017.

Emergence of drug resistance-associated mutations in HIV-1 subtype C protease gene in north India.印度北部HIV-1 C亚型蛋白酶基因中耐药相关突变的出现

Virus Genes. 2013 Dec;47(3):422-8. doi: 10.1007/s11262-013-0961-8. Epub 2013 Jul 26.

Differences in reversion of resistance mutations to wild-type under structured treatment interruption and related increase in replication capacity.结构治疗中断下耐药突变体向野生型的回复差异及相关复制能力的增加。

PLoS One. 2011 Jan 31;6(1):e14638. doi: 10.1371/journal.pone.0014638.

Enantiomeric radiochemical synthesis of R and S (1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid (FPMPA).R和S（1-(6-氨基-9H-嘌呤-9-基)-3-氟丙-2-基氧基）甲基膦酸（FPMPA）的对映体放射化学合成

J Labelled Comp Radiopharm. 2008 Mar 13;51(4):187-194. doi: 10.1002/jlcr.1505.

Host sequence motifs shared by HIV predict response to antiretroviral therapy.人类免疫缺陷病毒（HIV）共有的宿主序列基序可预测对抗逆转录病毒疗法的反应。

BMC Med Genomics. 2009 Jul 23;2:47. doi: 10.1186/1755-8794-2-47.

The impact of individual human immunodeficiency virus type 1 protease mutations on drug susceptibility is highly influenced by complex interactions with the background protease sequence.个体人类免疫缺陷病毒1型蛋白酶突变对药物敏感性的影响，受到与背景蛋白酶序列复杂相互作用的高度影响。

J Virol. 2009 Sep;83(18):9512-20. doi: 10.1128/JVI.00291-09. Epub 2009 Jul 8.

Alternative methods to analyse the impact of HIV mutations on virological response to antiviral therapy.分析HIV突变对抗病毒治疗病毒学反应影响的替代方法。

BMC Med Res Methodol. 2008 Oct 22;8:68. doi: 10.1186/1471-2288-8-68.

Active site binding and sequence requirements for inhibition of HIV-1 reverse transcriptase by the RT1 family of single-stranded DNA aptamers.单链DNA适配体RT1家族抑制HIV-1逆转录酶的活性位点结合及序列要求

Nucleic Acids Res. 2007;35(15):5039-50. doi: 10.1093/nar/gkm420. Epub 2007 Jul 21.

Protease inhibitor associated mutations compromise the efficacy of therapy in human immunodeficiency virus-1 (HIV-1) infected pediatric patients: a cross-sectional study.蛋白酶抑制剂相关突变会损害人类免疫缺陷病毒1型（HIV-1）感染的儿科患者的治疗效果：一项横断面研究。

AIDS Res Ther. 2007 Jul 9;4:15. doi: 10.1186/1742-6405-4-15.

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Update of the drug resistance mutations in HIV-1: 2004.

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