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八旬老人心脏手术围手术期死亡率较低。

Low perioperative mortality for cardiac surgery in octogenarians.

作者信息

Zangrillo A, Sparicio D, Crivellari M, Aletti G, Bove T, Mamo D, Bignami E, Marino G, Landoni G

机构信息

Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Vita-Salute University, Milan, Italy.

出版信息

Minerva Anestesiol. 2004 Oct;70(10):717-23; 723-6.

Abstract

AIM

The number of cardiac operations in octogenarians is steadily increasing. A review of personal 4 years' experience is made in order to identify which variables are associated to a poor prognosis in this high risk population.

METHODS

Perioperative variables and short-term outcome of 109 consecutive octogenarians were prospectively collected in a database. Data were analysed with descriptive statistics. Univariate and multivariate analyses were performed to identify preoperative risk factors for prolonged mechanical ventilation and ICU stay.

RESULTS

The 109 octogenarians represented 1.8% of the 4 940 cardiac operations performed at our University Teaching Hospital in the period January 1998-June 2001: 94 patients had comorbidities (86%); 46 underwent valve surgery (42%), 38 had coronary artery bypass grafting surgery (36%), and combined procedures or aortic arch replacement were performed in 25 patients (22%). Two patients died (1.8%). Postoperative complications included: myocardial infarction (10 patients, 9%), stroke (6 patients, 5%), renal replacement therapy (1 patient, 1%). Sixty nine patients (63%) had an uneventful perioperative period (63%). On a multivariate analysis, cardiopulmonary bypass (CPB) time was associated with prolonged intubation and ICU stay; mitral pathology predicted prolonged intubation while previous cardiac surgery was associated with prolonged ICU stay.

CONCLUSION

The 109 octogenarians studied had an excellent course in the immediate postoperative period. Therefore, on the basis of personal experience cardiac surgery could be safely performed in octogenarians.

摘要

目的

八十多岁老人接受心脏手术的数量在稳步增加。回顾个人4年的经验,以确定在这个高风险人群中哪些变量与预后不良相关。

方法

前瞻性地收集109例连续的八十多岁老人的围手术期变量和短期结果,并录入数据库。采用描述性统计分析数据。进行单因素和多因素分析,以确定延长机械通气和入住重症监护病房(ICU)的术前危险因素。

结果

109例八十多岁老人占1998年1月至2001年6月在我们大学教学医院进行的4940例心脏手术的1.8%:94例患者有合并症(86%);46例接受瓣膜手术(42%),38例进行冠状动脉搭桥手术(36%),25例患者进行联合手术或主动脉弓置换(22%)。2例患者死亡(1.8%)。术后并发症包括:心肌梗死(10例患者,9%)、中风(6例患者,5%)、肾脏替代治疗(1例患者,1%)。69例患者(63%)围手术期情况平稳(63%)。多因素分析显示,体外循环(CPB)时间与延长插管时间和入住ICU时间相关;二尖瓣病变预示插管时间延长,而既往心脏手术与入住ICU时间延长相关。

结论

所研究的109例八十多岁老人术后近期过程良好。因此,基于个人经验,八十多岁老人可以安全地接受心脏手术。

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