Chan Yvonne, Irish Jonathan C, Wood Stephen J, Sommer Doron D, Brown Dale H, Gullane Patrick J, O'Sullivan Brian, Lockwood Gina A
Department of Otolaryngology/Department of Surgical Oncology, Wharton Head and Neck Centre, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada.
J Otolaryngol. 2004 Apr;33(2):75-81. doi: 10.2310/7070.2004.00075.
To determine patients' smoking status after the diagnosis and treatment of squamous cell carcinoma of the head and neck (SCCHN) and to identify factors associated with smoking cessation.
Cross-sectional survey study conducted over a 2-year period.
Head and neck surgery clinic of an academic tertiary care hospital.
Two hundred thirteen consecutive patients diagnosed with SCCHN were interviewed to ascertain patients' smoking status and the incidence of smoking cessation. Information on demographics, tobacco and alcohol history, disease characteristics, and treatment modality was also collected.
The rate of smoking cessation was evaluated, in which smoking cessation is defined as the use of no cigarettes at least 1 month prior to the interview. Possible predictors of smoking cessation were evaluated.
One hundred twenty-five patients were found to be smoking at the time of diagnosis. Among these patients, 53.6% stopped smoking after diagnosis or during treatment. In the univariate analyses, tumour site (p = .01), concurrent alcohol use (p = .03), and number of attempts to quit pre- (p = .03) and postdiagnosis (p = .001) were found to be highly predictive of patient smoking cessation. Multivariable modelling showed that gender, tumour site, and number of attempts to quit smoking were significantly and independently related to smoking cessation.
Although smoking cessation would be presumed to be high after cancer diagnosis, this study has identified patient subgroups in which postdiagnosis smoking cessation intervention programs need to be made more effective.
确定头颈部鳞状细胞癌（SCCHN）诊断和治疗后患者的吸烟状况，并识别与戒烟相关的因素。
为期2年的横断面调查研究。
一所学术性三级护理医院的头颈外科诊所。
对连续213例诊断为SCCHN的患者进行访谈，以确定患者的吸烟状况和戒烟发生率。还收集了有关人口统计学、烟草和酒精使用史、疾病特征及治疗方式的信息。
评估戒烟率，戒烟定义为在访谈前至少1个月未吸烟。评估戒烟的可能预测因素。
125例患者在诊断时吸烟。在这些患者中，53.6%在诊断后或治疗期间戒烟。在单因素分析中，肿瘤部位（p = 0.01）、同时饮酒（p = 0.03）以及诊断前（p = 0.03）和诊断后（p = 0.001）的戒烟尝试次数被发现是患者戒烟的高度预测因素。多变量建模显示性别、肿瘤部位和戒烟尝试次数与戒烟显著且独立相关。
尽管癌症诊断后戒烟率可能较高，但本研究确定了一些患者亚组，在这些亚组中，诊断后戒烟干预计划需要更有效。
