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[胰腺内分泌肿瘤的影像学检查]

[Imaging of endocrine tumours of the pancreas].

作者信息

Ba-ssalamah Ahmed, Schima Wolfgang

机构信息

Universitätsklinik für Radiodiagnostik, Universität Wien, Wien, Osterreich.

出版信息

Wien Klin Wochenschr. 2003;115 Suppl 2:50-5.

PMID:15518147
Abstract

Islet cell tumors are rare pancreatic or peripancreatic neoplasms that produce and secrete hormones to a variable degree. Neuroendocrine tumors of the pancreas can occur sporadically or in association with multiple endocrine neoplasia type 1 (MEN I). Biologically active neuroendocrine tumors produce early symptoms and are often difficult to diagnose owing to their small dimensions, whereas biologically inactive forms are often large and sometimes found by chance. Imaging has a major role in the preoperative localization of the primary tumor and detection of metastases, providing an anatomic substrate whereas it plays a primary role in the regional staging of these neoplasm, for which surgery is the first and essential therapeutic approach. Several techniques are available including computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound, intraoperative ultrasound, somatostatin receptor scintigraphy, and arterial stimulation with venous sampling; each with unique advantages and certain limitations. Recent technical advances in Multidetector CT, and dynamic MRI using breath hold sequences have improved the sensitivity of these modalities markedly.

摘要

胰岛细胞瘤是罕见的胰腺或胰腺周围肿瘤,能不同程度地产生和分泌激素。胰腺神经内分泌肿瘤可散发性发生,或与1型多发性内分泌肿瘤(MEN I)相关。具有生物活性的神经内分泌肿瘤会产生早期症状,且由于其体积小,往往难以诊断,而无生物活性的肿瘤通常体积较大,有时是偶然发现的。影像学在原发性肿瘤的术前定位和转移灶检测中起着主要作用,提供解剖学依据,同时在这些肿瘤的区域分期中起主要作用,手术是首要且关键的治疗方法。有多种技术可供使用,包括计算机断层扫描(CT)、磁共振成像(MRI)、内镜超声、术中超声、生长抑素受体闪烁显像以及动脉刺激静脉采血;每种技术都有独特的优势和一定的局限性。多层螺旋CT和使用屏气序列的动态MRI的最新技术进展显著提高了这些检查方法的敏感性。

相似文献

1
[Imaging of endocrine tumours of the pancreas].[胰腺内分泌肿瘤的影像学检查]
Wien Klin Wochenschr. 2003;115 Suppl 2:50-5.
2
[Imaging of neuroendocrine tumors of the pancreas].[胰腺神经内分泌肿瘤的影像学检查]
Radiologe. 2003 Apr;43(4):293-300. doi: 10.1007/s00117-003-0885-8.
3
Imaging and localization of islet-cell tumours of the pancreas on CT and MRI.胰腺胰岛细胞瘤在CT和MRI上的成像与定位
Best Pract Res Clin Endocrinol Metab. 2005 Jun;19(2):195-211. doi: 10.1016/j.beem.2004.11.013.
4
Imaging of neuroendocrine tumours (CT/MR/US).神经内分泌肿瘤的影像学检查(CT/MR/US)
Best Pract Res Clin Endocrinol Metab. 2007 Mar;21(1):43-68. doi: 10.1016/j.beem.2007.01.003.
5
Endocrine tumors of the pancreas.胰腺内分泌肿瘤
Curr Opin Gen Surg. 1994:186-94.
6
[Morphological imaging of gastroenteropancreatic neuroendocrine tumours].[胃肠胰神经内分泌肿瘤的形态学成像]
Minerva Endocrinol. 2001 Sep;26(3):123-8.
7
Imaging of neuroendocrine tumors of the pancreas.胰腺神经内分泌肿瘤的影像学检查
Int J Gastrointest Cancer. 2001;30(1-2):73-85. doi: 10.1385/ijgc:30:1-2:073.
8
[Diagnostics and treatment in functional pancreatic neuroendocrine tumours].[功能性胰腺神经内分泌肿瘤的诊断与治疗]
Dtsch Med Wochenschr. 2011 Jun;136(24):1319-30. doi: 10.1055/s-0031-1280554. Epub 2011 Jun 7.
9
Pancreatic endocrine tumors.胰腺内分泌肿瘤。
Semin Oncol. 2010 Dec;37(6):594-618. doi: 10.1053/j.seminoncol.2010.10.014.
10
[Primary hyperparathyroidism, adrenal tumors and neuroendocrine tumors of the pancreas--clinical diagnosis and imaging requirements].[原发性甲状旁腺功能亢进、肾上腺肿瘤及胰腺神经内分泌肿瘤——临床诊断与影像学要求]
Radiologe. 2003 Apr;43(4):265-74. doi: 10.1007/s00117-003-0878-7.

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