Vinella D, Jaffé A, D'Ari R, Kohiyama M, Hughes P
Institut Jacques Monod, Centre National de la Recherche Scientifique, Université Paris, France.
J Bacteriol. 1992 Apr;174(7):2388-90. doi: 10.1128/jb.174.7.2388-2390.1992.
Escherichia coli dam mutants, lacking the GATC DNA methylase, do not produce anucleate cells at high frequencies, suggesting that hemimethylation of the chromosome origin of replication, oriC, is not essential for correct chromosome partitioning.
缺乏GATC DNA甲基化酶的大肠杆菌dam突变体不会高频产生无核细胞,这表明染色体复制起点oriC的半甲基化对于正确的染色体分配并非必不可少。