Chung Tommy, Yiannikas John, Lee Lincoln C L, Lau George T, Kritharides Leonard
Department of Cardiology, Concord Hospital, University of Sydney, Concord, New South Wales, Australia.
Am J Cardiol. 2004 Nov 1;94(9):1214-6. doi: 10.1016/j.amjcard.2004.07.102.
We present a series of 9 adults in 2 families with isolated noncompaction of the ventricular myocardium involving the left ventricular apex. Three of these patients had been previously misdiagnosed as having dilated cardiomyopathy, apical hypertrophic cardiomyopathy, or apical mural thrombus. Phenotypic variation was observed with gradation of severity of noncompaction and left ventricular systolic dysfunction between first-degree relatives.
我们报告了来自两个家族的9例成年患者，他们均患有累及左心室心尖的孤立性心室心肌致密化不全。其中3例患者之前被误诊为扩张型心肌病、心尖肥厚型心肌病或心尖壁血栓。在一级亲属中观察到了表型变异，表现为心肌致密化不全和左心室收缩功能障碍的严重程度存在梯度差异。
