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脊髓损伤患者的重度抑郁症症状:对筛查的启示

Symptoms of major depression in people with spinal cord injury: implications for screening.

作者信息

Bombardier Charles H, Richards J Scott, Krause James S, Tulsky David, Tate Denise G

机构信息

Rehabilitation Medicine, University of Washington School of Medicine, Seattle, USA.

出版信息

Arch Phys Med Rehabil. 2004 Nov;85(11):1749-56. doi: 10.1016/j.apmr.2004.07.348.

DOI:10.1016/j.apmr.2004.07.348
PMID:15520969
Abstract

OBJECTIVES

To provide psychometric data on a self-report measure of major depressive disorder (MDD) and to determine whether somatic symptoms are nonspecific or count toward the diagnosis.

DESIGN

Survey.

SETTING

Data from the National Spinal Cord Injury Statistical Center representing 16 Model Spinal Cord Injury Systems.

PARTICIPANTS

Eight hundred forty-nine people with spinal cord injury who completed a standardized follow-up evaluation 1 year after injury.

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURES

The Patient Health Questionnaire-9 (PHQ-9), a measure of MDD as defined by the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition . We computed descriptive statistics on rates of depressive symptoms and probable MDD, evaluated internal consistency and construct validity, and analyzed the accuracy of individual items as predictors of MDD.

RESULTS

Exactly 11.4% of participants met criteria for probable MDD. Probable MDD was associated with poorer subjective health, lower satisfaction with life, and more difficulty in daily role functioning. Probable MDD was not related to most demographic or injury-related variables. Both somatic and psychologic symptoms predicted probable MDD.

CONCLUSIONS

The PHQ-9 has promise as a tool with which to identify probable MDD in people with SCI. Somatic symptoms should be counted toward the diagnosis and should alert health care providers to the likelihood of MDD. More efficient screening is only one of the quality improvement efforts needed to enhance management of MDD.

摘要

目的

提供关于重度抑郁症(MDD)自我报告测量的心理测量数据,并确定躯体症状是无特异性的还是有助于诊断。

设计

调查。

设置

来自国家脊髓损伤统计中心的数据,代表16个脊髓损伤示范系统。

参与者

849名脊髓损伤患者,他们在受伤1年后完成了标准化的随访评估。

干预措施

不适用。

主要观察指标

患者健康问卷-9(PHQ-9),这是一种根据《精神障碍诊断与统计手册》第4版定义的MDD测量方法。我们计算了抑郁症状发生率和可能的MDD的描述性统计数据,评估了内部一致性和结构效度,并分析了各个项目作为MDD预测指标的准确性。

结果

恰好11.4%的参与者符合可能的MDD标准。可能的MDD与较差的主观健康状况、较低的生活满意度以及日常角色功能方面的更多困难相关。可能的MDD与大多数人口统计学或与损伤相关的变量无关。躯体症状和心理症状均能预测可能的MDD。

结论

PHQ-9有望作为一种工具,用于识别脊髓损伤患者中可能的MDD。躯体症状应计入诊断,并应提醒医疗保健提供者注意MDD的可能性。更有效的筛查只是加强MDD管理所需的质量改进措施之一。

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