Klimaszyk Dorota, Wilczek Leszek
Oddział Chorób Wewnetrznych i Ostrych Zatruć im. dr W. Błeńskiej, Szpital im. F. Raszei w Poznaniu.
Przegl Lek. 2004;61(4):385-8.
So far 5 cases of severe acute liver failure in the course of Amanita phalloides poisoning, treated in Department of Toxicology in Poznań were regarded for need of liver transplantation. In September 2001, 4 patients were directed to transplantology center: 3 adult persons were treated in Department of General Surgery and Liver Diseases, Medical University of Warsaw, and one 15-year-old boy in Department of Pediatric Surgery and Organ Transplantation, Children's Memorial Health Institute in Warsaw. According to King's College Hospital criteria a family of three qualified for liver transplantation. 40-year-old mother died during transplantation, 41-year old father and his 15-year old son underwent operation successfully. Two years after liver transplantation these two men were admitted to Department of Toxicology in Poznań for their clinical status assessment. Based on observations made in Department of Toxicology we conclude the management of patients who meet the clinical indicators of poor prognosis should be discussed with a transplantology center in the early stage of severe acute liver failure.
到目前为止,波兹南毒理学系收治的5例毒鹅膏中毒所致严重急性肝衰竭患者被认为需要进行肝移植。2001年9月,4名患者被送往移植中心:3名成年人在华沙医科大学普通外科和肝病科接受治疗,1名15岁男孩在华沙儿童纪念健康研究所小儿外科和器官移植科接受治疗。根据国王学院医院标准,一家三口符合肝移植条件。40岁的母亲在移植过程中死亡,41岁的父亲和他15岁的儿子手术成功。肝移植两年后,这两名男子因临床状况评估被送往波兹南毒理学系。基于毒理学系的观察结果,我们得出结论,对于符合预后不良临床指标的患者,应在严重急性肝衰竭早期与移植中心讨论治疗方案。