Pawłowska Joanna, Pawlak Jacek, Kamiński Andrzej, Hevelke Piotr, Jankowska Irena, Teisseyre Mikołaj, Szymczak Marek, Kalicińiski Piotr, Krawczyk Marek
Kliniki Gastroenterologii, Hepatologii i Immunologii, Instytutu Pomnik-Centrum Zdrowia Dziecka w Warszawie.
Wiad Lek. 2006;59(1-2):131-4.
Amanita phalloides poisoning is one of the most dramatic medical invents. The course of the illness may vary from mild to the lethal, with signs of fulminant liver insufficiency with coma and multiorgan failure. When hepatic encephalopathy (III/IV degrees) occurs the prognosis is very poor. In definite cases the liver transplantation is necessary. The authors present severe Amanita phalloides poisoning in three family members, who due to fulminant hepatic failure underwent liver transplantation. The two of them (son and father) transplanted accordingly in fifth and seventh day after poisoning, survived. Mother, in whom transplantation started in ninth day after poisoning, died intraoperativel with signs of massive hemorrhage, and cardiac arrest.
毒鹅膏中毒是最严重的医疗急症之一。病程可能从轻微到致命,伴有暴发性肝衰竭、昏迷和多器官功能衰竭的症状。当发生肝性脑病(III/IV度)时,预后非常差。在某些明确的病例中,肝移植是必要的。作者介绍了三名家庭成员发生的严重毒鹅膏中毒病例,他们因暴发性肝衰竭接受了肝移植。其中两人(儿子和父亲)在中毒后的第五天和第七天分别接受了移植,存活了下来。母亲在中毒后的第九天开始进行移植手术,术中死于大出血和心脏骤停。