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[纯化技术在癌症基因组学研究中的应用与发展]

[Application and development of purification in cancer genomics research].

作者信息

Liu Zhong-Qi, Tian Yong-Quan

机构信息

Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan 410 078, P.R. China.

出版信息

Ai Zheng. 2004 Nov;23(11):1357-60.

Abstract

In the study of cancer genomics, a series of purification methods have been invented to collect homogenous cells from heterogeneous cancerated tissue. Tissue microdissection methods, such as manual microdissection, mechanical microdissection, and laser technology, accelerated cancer genomics research. Each method holds both advantage and disadvantage, the selection of methods depends on the demands of study, and the instruments used in study.

摘要

在癌症基因组学研究中,已经发明了一系列纯化方法,用于从异质性癌变组织中收集同质细胞。组织显微切割方法,如手动显微切割、机械显微切割和激光技术,加速了癌症基因组学研究。每种方法都有其优缺点,方法的选择取决于研究需求以及研究所使用的仪器。

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