Herz P R, Chen Y, Aguirre A D, Schneider K, Hsiung P, Fujimoto J G, Madden K, Schmitt J, Goodnow J, Petersen C
Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Opt Lett. 2004 Oct 1;29(19):2261-3. doi: 10.1364/ol.29.002261.
A distally actuated, rotational-scanning micromotor endoscope catheter probe is demonstrated for ultrahigh-resolution in vivo endoscopic optical coherence tomography (OCT) imaging. The probe permits focus adjustment for visualization of tissue morphology at varying depths with improved transverse resolution compared with standard OCT imaging probes. The distal actuation avoids nonuniform scanning motion artifacts that are present with other probe designs and can permit a wider range of imaging speeds. Ultrahigh-resolution endoscopic imaging is demonstrated in a rabbit with <4-microm axial resolution by use of a femtosecond Cr:forsterite laser light source. The micromotor endoscope catheter probe promises to improve OCT imaging performance in future endoscopic imaging applications.
本文展示了一种用于超高分辨率体内内镜光学相干断层扫描（OCT）成像的远端驱动旋转扫描微电机内窥镜导管探头。与标准OCT成像探头相比，该探头可进行焦点调整，以观察不同深度的组织形态，横向分辨率更高。远端驱动避免了其他探头设计中存在的不均匀扫描运动伪影，并可实现更广泛的成像速度范围。通过使用飞秒Cr:镁橄榄石激光光源，在一只兔子身上实现了轴向分辨率小于4微米的超高分辨率内镜成像。这种微电机内窥镜导管探头有望在未来的内镜成像应用中提高OCT成像性能。
