Kobayashi Yuka, Morisawa Fumi, Saigo Kazuhiko
Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Org Lett. 2004 Nov 11;6(23):4227-30. doi: 10.1021/ol0483145.
An enantiopure phosphonothioic acid showed a unique and superior chiral recognition ability, arising from its P-stereogenicity, for racemic 1-phenylethylamine derivatives through diastereomeric crystallization. Spherical molecular clusters, associated by hydrogen bonds and CH/pi interactions, aggregated with high symmetry in the less-soluble diastereomeric salts.
一种对映体纯的硫代膦酸因其P-立体中心性，通过非对映异构结晶对消旋1-苯乙胺衍生物表现出独特且优异的手性识别能力。由氢键和CH/π相互作用关联的球形分子簇在较难溶解的非对映异构盐中以高度对称性聚集。
