钯催化的芳基三乙铵双（儿茶酚）硅酸盐与芳基溴化物在微波辐射下的交叉偶联反应。

Palladium-catalyzed cross-coupling of aryl triethylammonium bis(catechol) silicates with aryl bromides using microwave irradiation.

作者信息

Seganish W Michael, DeShong Philip

机构信息

Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20770, USA.

出版信息

Org Lett. 2004 Nov 11;6(23):4379-81. doi: 10.1021/ol048044q.

DOI:10.1021/ol048044q

PMID:15524488

Abstract

The scope of the palladium-catalyzed cross-coupling reaction of aryl bis(catechol) silicates has been extended to include the coupling of aryl bromides by employing microwave irradiation. This new set of coupling conditions is tolerant of electron-rich and -deficient aryl bromides. In addition, a variety of substituted aryl bis(catechol) silicates have been successfully cross-coupled.

摘要

芳基双（邻苯二酚）硅酸酯的钯催化交叉偶联反应范围已扩展至通过微波辐射实现芳基溴化物的偶联。这套新的偶联条件对富电子和缺电子芳基溴化物均具有耐受性。此外，多种取代的芳基双（邻苯二酚）硅酸酯已成功实现交叉偶联。