Ruan Jiwu, Saidi Ourida, Iggo Jonathan A, Xiao Jianliang
Department of Chemistry, Liverpool Centre for Materials and Catalysis, University of Liverpool, Liverpool L69 7ZD, UK.
J Am Chem Soc. 2008 Aug 13;130(32):10510-1. doi: 10.1021/ja804351z. Epub 2008 Jul 18.
A new protocol for the direct acylation of aryl bromides with aldehydes is established. It appears to involve palladium-amine cooperative catalysis, affording synthetically important alkyl aryl ketones in moderate to excellent yields in a straightforward manner, and broadening the scope of metal-catalyzed coupling reactions.
建立了一种芳基溴与醛直接酰化的新方案。它似乎涉及钯 - 胺协同催化，以直接的方式以中等至优异的产率提供具有重要合成价值的烷基芳基酮，并拓宽了金属催化偶联反应的范围。
