Lyons-Warren Ariel, Lillie Rema, Hershey Tamara
Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Dev Neuropsychol. 2004;26(3):661-78. doi: 10.1207/s15326942dn2603_1.
Delayed response paradigms have been used to examine the neural basis of short and long-term memory in humans. However, limited information exists on how delayed response performance changes across the lifespan. Using a well-validated spatial delayed response (SDR) task, we examined performance at short and long delays in over 300 control participants, 7 to 80 years old. We found a significant nonlinear relation between age and short delay performance (children and older adults worse than young adults) and a significant effect of delay length across the entire lifespan (long worse than short; largest in the youngest children, diminishing nonlinearly with age). This study compares short and long-term spatial memory and suggests that the relation between these systems may alter across the lifespan.
延迟反应范式已被用于研究人类短期和长期记忆的神经基础。然而，关于延迟反应表现如何随寿命变化的信息有限。我们使用经过充分验证的空间延迟反应（SDR）任务，对300多名7至80岁的对照参与者在短期和长期延迟情况下的表现进行了研究。我们发现年龄与短期延迟表现之间存在显著的非线性关系（儿童和老年人比年轻人差），并且延迟长度在整个寿命期间有显著影响（长期比短期差；在最年幼的儿童中最大，随年龄呈非线性递减）。这项研究比较了短期和长期空间记忆，并表明这些系统之间的关系可能会随寿命而改变。
