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老年精神分裂症患者:农村集水区的一项社区研究。

Older people with schizophrenia: a community study in a rural catchment area.

作者信息

Rodriguez-Ferrera Silvia, Vassilas Christopher A, Haque Sayeed

机构信息

West Suffolk Hospital, Bury St Edmunds, UK.

出版信息

Int J Geriatr Psychiatry. 2004 Dec;19(12):1181-7. doi: 10.1002/gps.1237.

Abstract

BACKGROUND

An increasing number of older people with schizophrenia are living in the community but we still have little data on their clinical presentation, service use and functioning.

METHODS

All patients over the age of 60 years with a primary diagnosis of a non-affective psychotic disorder who were known to health services were identified in a rural area of East England. Subjects were interviewed with the Present State Examination and other standardised interview instruments.

RESULTS

Seventy-two subjects fulfilled study inclusion criteria. Forty-six of these had first become ill before the age of 60 years and 26 after (the very late onset group (VLO)). Eighty per cent were women and 26% had never married. Eighty-seven per cent lived in their own homes and 51% alone. In the preceding month, 41% of the sample had experienced psychotic symptoms and 15% depressive symptoms. Twenty-seven per cent of the sample were cognitively impaired. The earlier onset group had significantly higher rates of tardive dyskinesia and negative symptoms of schizophrenia and were treated with higher doses of neuroleptics. The VLO group had higher rates of hearing impairment (54% vs 15% p = 0.001) and of partial or no insight (93% vs 55% p = 0.004).

CONCLUSIONS

Despite significant differences in presentation, elderly patients with schizophrenia and very late onset schizophrenia-like psychosis have much in common. Both groups are vulnerable with high levels of psychopathology, poor insight, sensory impairment and social isolation. The needs of older people with schizophrenia must be taken into account when services for older adults are planned.

摘要

背景

越来越多患有精神分裂症的老年人生活在社区中,但我们对他们的临床表现、服务利用情况和功能状况仍知之甚少。

方法

在英格兰东部的一个农村地区,确定了所有年龄在60岁以上、主要诊断为非情感性精神障碍且为卫生服务机构所知的患者。采用现况检查和其他标准化访谈工具对受试者进行访谈。

结果

72名受试者符合研究纳入标准。其中46人在60岁之前首次发病,26人在60岁之后发病(极晚发组(VLO))。80%为女性,26%从未结婚。87%的人住在自己家里,51%独自生活。在前一个月,41%的样本出现过精神病症状,15%出现过抑郁症状。27%的样本存在认知障碍。早发组迟发性运动障碍和精神分裂症阴性症状的发生率显著更高,且接受的抗精神病药物剂量更高。极晚发组听力障碍发生率更高(54%对15%,p = 0.001),部分自知力或无自知力的发生率更高(93%对55%,p = 0.004)。

结论

尽管临床表现存在显著差异,但患有精神分裂症的老年患者和极晚发精神分裂症样精神病患者有许多共同之处。两组患者都易患严重精神疾病,自知力差,有感觉障碍和社会隔离问题。在规划老年人服务时,必须考虑到患有精神分裂症的老年人的需求。

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