Hui Xin-Ping, Chen Chien-An, Gau Han-Mou
Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan.
Chirality. 2005 Jan;17(1):51-6. doi: 10.1002/chir.20094.
A series of N-sulfonylated amino alcohols were prepared and the enantioselective addition of diethylzinc to aldehydes catalyzed by titanium(IV) complexes of those ligands were carried out. Excellent enantioselectivities were obtained for the desired alcohols with enantiomeric excess values up to 94% of R-configuration.
制备了一系列N-磺酰化氨基醇，并进行了由这些配体的钛（IV）配合物催化的二乙基锌对醛的对映选择性加成反应。对于所需的醇，获得了优异的对映选择性，对映体过量值高达R构型的94%。
