Mota Maria, Lichiardopol Corina, Mota E, Pănuş Camelia, Pănuş A
Department of Diabetes and Metabolic Diseases, University of Medicine and Pharmacy, 4, Petru Rareş Str., 1100 Craiova, Romania.
Rom J Intern Med. 2003;41(2):163-77.
Erectile dysfunction (ED) is 2-3 times more frequent in men with diabetes mellitus than in men without such a history and might be an early marker of endothelial dysfunction. We studied a group of 310 unselected male patients within the Clinical Center of Diabetes and Metabolic Diseases of Dolj County, with ages ranging between 20-78 years (57.43 + 0.835) and a positive history of diabetes mellitus for 1-47 years (10.09 +/- 8.715). Erectile dysfunction, quantified using SHIM (Sexual Health Inventory for Men), was present in 196 patients (63.2%); severe in 52 patients (16.8%), moderate in 42 patients (13.5%) and mild in 102 patients (32.9%). Erectile dysfunction showed a positive correlation with age after 65 years, history of diabetes of more than 10 years, obesity, stroke, arteriopathy, retinopathy, neuropathy and the smoking habit and was not correlated to the type of diabetes mellitus, history of diabetes less than 10 years, diabetes therapy, hypertension, ischemic heart disease, nephropathy, dyslipidemia and alcohol consumption. Our results plead for a holistic approach of the diabetic patient, irrespective of age, in order to detect and to treat all the risk factors, keeping in mind that the appearance of erectile dysfunction might indicate the presence of occult chronic diabetes complications.
勃起功能障碍(ED)在糖尿病男性患者中的发生率是无糖尿病病史男性的2至3倍,可能是内皮功能障碍的早期标志。我们在多尔日县糖尿病与代谢疾病临床中心研究了一组310名未经挑选的男性患者,年龄在20至78岁之间(57.43±0.835),糖尿病病史为1至47年(10.09±8.715)。使用男性性功能健康问卷(SHIM)对勃起功能障碍进行量化评估,结果显示196名患者(63.2%)存在勃起功能障碍;其中重度52例(16.8%),中度42例(13.5%),轻度102例(32.9%)。勃起功能障碍与65岁以后的年龄、糖尿病病史超过10年、肥胖、中风、动脉病、视网膜病变、神经病变以及吸烟习惯呈正相关,与糖尿病类型、糖尿病病史少于10年、糖尿病治疗、高血压、缺血性心脏病、肾病、血脂异常和饮酒无关。我们的研究结果表明,无论年龄大小,都应对糖尿病患者采取整体治疗方法,以便检测和治疗所有风险因素,同时要记住勃起功能障碍的出现可能表明存在隐匿性慢性糖尿病并发症。