Gnjidić Zivko
Klinika za neurokirugiju, Klinicka bolnica Sestre milosrdnice, Zagreb.
Lijec Vjesn. 2004 Jan-Feb;126(1-2):26-31.
Due to improved diagnostics, and primarily neuroradiological methods, an increased incidence of sellar region tumors is marked, among which the most common are pituitary adenomas. Sellar region tumors cause dysfunctions of the hypothalamo-pituitary axis as well as surrounding neurovascular structures. Despite the development of pharmacological and radiation therapy, surgical treatment is in these cases still a dominant therapeutical method. The author displays an overview of contemporary surgical methods for the treatment of sellar region tumors, as well as an overview of other adjuvant methods, especially pharmacological. Described are the results of over 1200 patients surgically treated during the past 20 years for sellar region tumors, as well as their complications and adverse effects. The author argues for respecting modem consensus on standardization of results of treating sellar region tumors as well as the consensus on professional and technical equipment of doctors and institutions that deal with this complex work.
由于诊断技术的改进,主要是神经放射学方法的进步,鞍区肿瘤的发病率明显上升,其中最常见的是垂体腺瘤。鞍区肿瘤会导致下丘脑 - 垂体轴以及周围神经血管结构功能障碍。尽管药物治疗和放射治疗有所发展,但在这些病例中手术治疗仍然是主要的治疗方法。作者展示了当代治疗鞍区肿瘤的手术方法概述,以及其他辅助方法,特别是药物治疗方法的概述。描述了过去20年中1200多名接受手术治疗的鞍区肿瘤患者的治疗结果、并发症和不良反应。作者主张遵循关于鞍区肿瘤治疗结果标准化的现代共识,以及关于从事这项复杂工作的医生和机构的专业和技术设备的共识。