Hancock Rebecca, Koren Gideon
Motherisk Program, Hospital for Sick Children, Toronto, Ont.
Can Fam Physician. 2004 Oct;50:1361-3.
One of my patients was diagnosed with celiac disease and maintains a strict gluten-free diet. Is her fetus at risk of neural tube defects because she does not get folic acid from bread and other flour-based foods?
A woman with celiac disease must supplement her diet with multivitamins, including folic acid. Most prenatal vitamins contain 0.8 to 0.9 mg of folic acid, double the amount recommended by Health Canada for prevention of neural tube defects. Without supplementation (eg, undiagnosed pregnancy), women with celiac disease might not take in enough folate to maintain protective levels.
我的一位患者被诊断出患有乳糜泻，一直严格遵循无麸质饮食。由于她无法从面包和其他面粉类食物中获取叶酸，她的胎儿有神经管缺陷的风险吗？
患有乳糜泻的女性必须通过补充多种维生素，包括叶酸，来调整饮食。大多数产前维生素含有0.8至0.9毫克叶酸，是加拿大卫生部推荐的预防神经管缺陷剂量的两倍。如果不进行补充（例如，未确诊怀孕），患有乳糜泻的女性可能无法摄入足够的叶酸以维持保护水平。
