Petricci Elena, Mugnaini Claudia, Radi Marco, Corelli Federico, Botta Maurizio
Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100 Siena, Italy.
J Org Chem. 2004 Nov 12;69(23):7880-7. doi: 10.1021/jo048837q.
A microwave-assisted synthesis of solid-supported reagents for the acylation of amines has been developed, and the same methodology has been successfully applied to the preparation of acylating agents anchored on different solid supports. Similarly, alcohols, phenols, and thiophenols have been easily acylated using these reagents under microwave irradiation.