脑梗死第一年的卒中复发——鸟取大学腔隙性脑梗死预后研究（TULIPS）
Stroke recurrence within the first year following cerebral infarction--Tottori University Lacunar Infarction Prognosis Study (TULIPS).
作者信息
Soda Takao, Nakayasu Hiroyuki, Maeda Masanobu, Kusumi Masayoshi, Kowa Hisanori, Awaki Etsuko, Saito Jun, Nakashima Kenji
机构信息
Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan.
出版信息
Acta Neurol Scand. 2004 Dec;110(6):343-9. doi: 10.1111/j.1600-0404.2004.00290.x.
OBJECTIVES
To identify determinants of recurrence after ischemic stroke in the Japanese population.
MATERIALS AND METHODS
We enrolled 885 patients with acute ischemic stroke that had been admitted to our community hospitals. A total of 831 cases were followed for 1 year after the index stroke. Patients were assigned to one of the ischemic stroke subtype groups based on the NINDS Stroke Data Bank criteria.
RESULTS
Rates of stroke recurrence were significantly different among stroke subtype groups: 14.4% in cardioembolic infarction, 7.3% in atherothrombotic infarction (ATI), 6.2% in lacunar infarction (LI) and 7.8% in infarction of uncertain cause. Previous history of stroke was the predictor of stroke recurrence for the groups of ATI and LI patients, and diabetes mellitus was the predictor of recurrence for the group of LI patients.
CONCLUSION
The rate of recurrence and risk factors for stroke recurrence are different by stroke subtypes.
目的
确定日本人群缺血性中风后复发的决定因素。
材料与方法
我们纳入了885例入住我们社区医院的急性缺血性中风患者。共有831例患者在首次中风后随访1年。根据美国国立神经疾病与中风研究所（NINDS）中风数据库标准，将患者分配到缺血性中风亚型组之一。
结果
中风复发率在中风亚型组之间存在显著差异：心源性栓塞性梗死为14.4%，动脉粥样硬化血栓形成性梗死（ATI）为7.3%，腔隙性梗死（LI）为6.2%，病因不明的梗死为7.8%。中风病史是ATI组和LI组患者中风复发的预测因素，而糖尿病是LI组患者复发的预测因素。
结论
中风复发率和中风复发的危险因素因中风亚型而异。
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