Dorey Grace, Speakman Mark, Feneley Roger, Swinkels Annette, Dunn Christopher, Ewings Paul
The Somerset Nuffield Hospital, Taunton, UK.
Br J Gen Pract. 2004 Nov;54(508):819-25.
The pelvic floor muscles are active in normal erectile function. Therefore, it was hypothesised that weak pelvic floor muscles could be a cause of erectile dysfunction.
To compare the efficacy of pelvic floor muscle exercises and manometric biofeedback with lifestyle changes for men with erectile dysfunction.
Randomised controlled trial.
The Somerset Nuffield Hospital, Taunton, United Kingdom.
Fifty-five men with erectile dysfunction (median age 59.2 years; range 22-78 years) were enrolled from a local urology clinic. Of these, 28 participants were randomised to an intervention group and engaged in pelvic floor exercises, as well as receiving biofeedback and suggestions for lifestyle changes. Twenty-seven controls were solely advised on lifestyle changes. Baseline, 3- and 6-month assessments were: erectile function domain of International Index of Erectile Function (IIEF), Partner's International Index of Erectile Function (PIIEF), Erectile Dysfunction-Effect on Quality of Life (ED-EQoL), anal manometry, digital anal measurements, and clinical assessment by an assessor blind to treatment allocation. After 3 months, the control group were transferred to the active arm.
At 3 months, compared with controls, men in the intervention group showed significant mean increases in the erectile function domain of the IIEF (6.74 points, P = 0.004); anal pressure (44.16 cmH(2)O, P <0.001); and digital anal grades (1.5 grades, P <0.001). All showed further improvement in these outcomes at 6 months. Similar benefits were seen in men of the control arm after transfer to active treatment. A total of 22 (40.0%) participants attained normal function, 19 (34.5%) participants had improved erectile function, and 14 (25.5%) participants failed to improve.
Pelvic floor muscle exercises and biofeedback are an effective treatment for men with erectile dysfunction.
盆底肌肉在正常勃起功能中发挥作用。因此，有人提出假设，盆底肌肉薄弱可能是勃起功能障碍的一个原因。
比较盆底肌肉锻炼和压力测量生物反馈疗法与生活方式改变对勃起功能障碍男性的疗效。
随机对照试验。
英国汤顿的萨默塞特纳菲尔德医院。
从当地一家泌尿外科诊所招募了55名勃起功能障碍男性（中位年龄59.2岁；范围22 - 78岁）。其中，28名参与者被随机分配到干预组，进行盆底肌肉锻炼，并接受生物反馈以及生活方式改变的建议。27名对照组参与者仅得到生活方式改变的建议。基线、3个月和6个月的评估指标包括：国际勃起功能指数（IIEF）的勃起功能领域、伴侣国际勃起功能指数（PIIEF）、勃起功能障碍对生活质量的影响（ED - EQoL）、肛门压力测量、手指肛门测量以及由对治疗分配不知情的评估者进行的临床评估。3个月后，对照组被转至治疗组。
3个月时，与对照组相比，干预组男性在IIEF的勃起功能领域平均得分显著增加（6.74分，P = 0.004）；肛门压力（44.16 cmH₂O，P < 0.001）；以及手指肛门分级（1.5级，P < 0.001）。6个月时，所有这些指标均进一步改善。对照组转至治疗组后也出现了类似的改善。共有22名（40.0%）参与者达到正常功能，19名（34.5%）参与者勃起功能得到改善，14名（25.5%）参与者未得到改善。
盆底肌肉锻炼和生物反馈疗法是治疗勃起功能障碍男性的有效方法。
