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酒精性胰腺炎

Alcoholic pancreatitis.

作者信息

Hanck Christoph, Whitcomb David C

机构信息

Department of Medicine, University of Pittsburgh, UPMC Presbyterian, Mezzanine Level-C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

出版信息

Gastroenterol Clin North Am. 2004 Dec;33(4):751-65. doi: 10.1016/j.gtc.2004.07.002.

Abstract

Without doubt, alcohol consumption is one of the most important considerations in adults with acute or chronic pancreatitis. Understanding chronic pancreatitis as a complex disorder in which complimentary factors are required for recurrent acute and late chronic pancreatitis to develop in subsets of patients is critical for the early diagnosis and management of these individuals. Recent pathophysiological and genetic findings represent the beginning of major diagnostic and treatment breakthroughs that are likely to continue for the foreseeable future. The information provided in this article should provide the physician with a fresh perspective and remind the clinician of the importance of an accurate and complete history, and the need to document the actual alcohol consumption, pattern of drinking, and raise appropriate concerns if signs of alcoholism are detected. If alcohol-associated pancreatitis is detected, then limitation of pancreatic damage, limitation of progression, or preventative intervention should become the major concern.

摘要

毫无疑问,饮酒是患有急性或慢性胰腺炎的成年人最重要的考虑因素之一。将慢性胰腺炎理解为一种复杂的疾病,其中复发性急性和晚期慢性胰腺炎在部分患者中发展需要多种因素共同作用,这对于这些个体的早期诊断和管理至关重要。最近的病理生理学和遗传学研究结果代表了重大诊断和治疗突破的开端,在可预见的未来可能会持续下去。本文提供的信息应能为医生提供新的视角,并提醒临床医生准确完整病史的重要性,以及记录实际饮酒量、饮酒模式的必要性,如果检测到酗酒迹象,还需提出适当的担忧。如果检测到酒精相关性胰腺炎,那么限制胰腺损伤、限制病情进展或进行预防性干预应成为主要关注点。

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