Suzuki Mitsuo, Miyai Ichiro, Ono Takeshi, Oda Ichiro, Konishi Ikuo, Kochiyama Takanori, Kubota Kisou
Rehabilitation Department, Neurorehabilitation Research Institute, Bobath Memorial Hospital, 1-6-5, Higashinaka-hama, Joto-ku, Osaka 536-0023, Japan.
Neuroimage. 2004 Nov;23(3):1020-6. doi: 10.1016/j.neuroimage.2004.07.002.
We investigated changes of regional activation in the frontal cortices as assessed by changes of hemoglobin oxygenation during walking at 3 and 5 km/h and running at 9 km/h on a treadmill using a near-infrared spectroscopic (NIRS) imaging technique. During the acceleration periods immediately preceded reaching the steady walking or running speed, the levels of oxygenated hemoglobin (oxyHb) increased, but those of deoxygenated hemoglobin (deoxyHb) did not in the frontal cortices. The changes were greater at the higher locomotor speed in the bilateral prefrontal cortex and the premotor cortex, but there were less speed-associated changes in the sensorimotor cortices. The medial prefrontal activation was most prominent during the running task. These results indicate that the prefrontal and premotor cortices are involved in adapting to locomotor speed on the treadmill. These areas might predominantly participate in the control of running rather than walking.
我们使用近红外光谱（NIRS）成像技术，研究了在跑步机上以3公里/小时和5公里/小时的速度行走以及以9公里/小时的速度跑步时，额叶皮质区域激活的变化，该变化通过血红蛋白氧合的变化来评估。在即将达到稳定行走或跑步速度之前的加速阶段，额叶皮质中氧合血红蛋白（oxyHb）水平升高，但脱氧血红蛋白（deoxyHb）水平没有变化。在双侧前额叶皮质和运动前皮质中，较高运动速度时的变化更大，但感觉运动皮质中与速度相关的变化较小。在跑步任务期间，内侧前额叶激活最为显著。这些结果表明，前额叶和运动前皮质参与了对跑步机上运动速度的适应。这些区域可能主要参与跑步而非行走的控制。
