Corvini P F X, Meesters R J W, Schäffer A, Schröder H F, Vinken R, Hollender J
Department of Biology V, RWTH Aachen University, Aachen, Germany.
Appl Environ Microbiol. 2004 Nov;70(11):6897-900. doi: 10.1128/AEM.70.11.6897-6900.2004.
Sphingomonas sp. strain TTNP3 degrades 4(3',5'-dimethyl-3'-heptyl)-phenol and unidentified metabolites that were described previously. The chromatographic analyses of the synthesized reference compound and the metabolites led to their identification as 2(3',5'-dimethyl-3'-heptyl)-1,4-benzenediol. This finding indicates that the nonylphenol metabolism of this bacterium involves unconventional degradation pathways where an NIH shift mechanism occurs.
鞘氨醇单胞菌属菌株TTNP3可降解4(3',5'-二甲基-3'-庚基)苯酚及之前描述的未鉴定代谢物。对合成的参考化合物和代谢物进行色谱分析后,将它们鉴定为2(3',5'-二甲基-3'-庚基)-1,4-苯二酚。这一发现表明,该细菌的壬基酚代谢涉及发生NIH迁移机制的非常规降解途径。